The Dual Functions of Andrographolide in the Epstein–Barr Virus-Positive Head-and-Neck Cancer Cells: The Inhibition of Lytic Reactivation of the Epstein–Barr Virus and the Induction of Cell Death

The Dual Functions of Andrographolide in the Epstein–Barr Virus-Positive Head-and-Neck Cancer Cells: The Inhibition of Lytic Reactivation of the Epstein–Barr Virus and the Induction of Cell Death

Andrographolide, a medicinal compound, exhibits several pharmacological activities, including antiviral and anticancer properties. Previously, we reported that andrographolide inhibits Epstein–Barr virus (EBV) lytic reactivation, which is associated with viral transmission and oncogenesis in epithel...

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Bibliographic Details
Main Authors: Chukkris Heawchaiyaphum, Praphatson Malat, Chamsai Pientong, Sittiruk Roytrakul, Yodying Yingchutrakul, Sirinart Aromseree, Supawadee Suebsasana, Panupong Mahalapbutr, Tipaya Ekalaksananan
Format: Article
Language:English
Published: MDPI AG 2023-11-01
Series:International Journal of Molecular Sciences
Subjects:
andrographolide
EBV
EBV lytic reactivation
HDAC5
MEF2D
SP1
Online Access:https://www.mdpi.com/1422-0067/24/21/15867

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