The Core Stem Genes <i>SOX2</i>, <i>POU5F1/OCT4</i>, and <i>NANOG</i> Are Expressed in Human Parathyroid Tumors and Modulated by <i>MEN1</i>, <i>YAP1</i>, and β-catenin Pathways Activation

The Core Stem Genes <i>SOX2</i>, <i>POU5F1/OCT4</i>, and <i>NANOG</i> Are Expressed in Human Parathyroid Tumors and Modulated by <i>MEN1</i>, <i>YAP1</i>, and β-catenin Pathways Activation

Tumors of the parathyroid glands are the second most common endocrine neoplasia. Epigenetic studies revealed an embryonic signature involved in parathyroid tumorigenesis. Here, we investigated the expression of the stem core genes <i>SOX2, POU5F1/OCT4,</i> and <i>NANOG</i>. R...

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Bibliographic Details
Main Authors: Chiara Verdelli, Annamaria Morotti, Giulia Stefania Tavanti, Rosamaria Silipigni, Silvana Guerneri, Stefano Ferrero, Leonardo Vicentini, Valentina Vaira, Sabrina Corbetta
Format: Article
Language:English
Published: MDPI AG 2021-06-01
Series:Biomedicines
Subjects:
parathyroid tumors
<i>SOX2</i>
<i>NANOG</i>
<i>POU5F1/OCT4</i>
<i>MEN1</i>
<i>YAP1</i>
Online Access:https://www.mdpi.com/2227-9059/9/6/637

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