A Natural CHI3L1—Targeting Compound, Ebractenoid F, Inhibits Lung Cancer Cell Growth and Migration and Induces Apoptosis by Blocking CHI3L1/AKT Signals

A Natural CHI3L1—Targeting Compound, Ebractenoid F, Inhibits Lung Cancer Cell Growth and Migration and Induces Apoptosis by Blocking CHI3L1/AKT Signals

Our previous big data analyses reported a strong association between CHI3L1 expression and lung tumor development. In this present study, we investigated whether a CHI3L1-inhibiting natural compound, ebractenoid F, inhibits lung cancer cell growth and migration and induces apoptosis. Ebractenoid F c...

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Bibliographic Details
Main Authors: Da Eun Hong, Ji Eun Yu, Jin Woo Lee, Dong Ju Son, Hee Pom Lee, Yuri Kim, Ju Young Chang, Dong Won Lee, Won Kyu Lee, Jaesuk Yun, Sang Bae Han, Bang Yeon Hwang, Jin Tae Hong
Format: Article
Language:English
Published: MDPI AG 2022-12-01
Series:Molecules
Subjects:
ebractenoid F
CHI3L1
AKT
lung cancer cell growth inhibition
Online Access:https://www.mdpi.com/1420-3049/28/1/329

Internet

https://www.mdpi.com/1420-3049/28/1/329

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