A rare case report of neonatal calcinosis cutis induced by distant and delayed extravasation of intravenous calcium gluconate

A 3,480 g male neonate showed tachypnea symptom with a serum ionized calcium level of 0.66 mmol/L by routine clinical analysis. He was injected calcium gluconate intravenously through femoral vein catheter to treat the hypocalcemia. On second day after the injection, he started to show erythema in t...

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Main Authors: Kwang Hyeon Ahn, Eun Soo Park
Format: Article
Language:English
Published: Thieme Medical Publishers, Inc. 2021-11-01
Series:Archives of Plastic Surgery
Subjects:
Online Access:http://www.thieme-connect.de/DOI/DOI?10.5999/aps.2020.01942
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author Kwang Hyeon Ahn
Eun Soo Park
author_facet Kwang Hyeon Ahn
Eun Soo Park
author_sort Kwang Hyeon Ahn
collection DOAJ
description A 3,480 g male neonate showed tachypnea symptom with a serum ionized calcium level of 0.66 mmol/L by routine clinical analysis. He was injected calcium gluconate intravenously through femoral vein catheter to treat the hypocalcemia. On second day after the injection, he started to show erythema in the flank area. The lesion became firm and changed into whitish crust consist of small crystals. Abdominal X-ray and ultrasonography showed the accumulation of calcium deposit in the subcutaneous layer of the lesion. Surgical debridement was performed to remove the crust with calcium deposit and acellular fish skin graft rich in omega-3 (Kerecis) was applied to the defect site for secondary intention of the defect wound. After 2 months, the skin and soft tissue defect were fully covered with healthy normal skin without depression or contracture. This report is a first case of iatrogenic calcinosis cutis without extravasation symptom.
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spelling doaj.art-8d5f708b7ca4427a99b1d170d1f346d92022-12-22T03:10:23ZengThieme Medical Publishers, Inc.Archives of Plastic Surgery2234-61632234-61712021-11-01480664164510.5999/aps.2020.019423916A rare case report of neonatal calcinosis cutis induced by distant and delayed extravasation of intravenous calcium gluconateKwang Hyeon Ahn0Eun Soo Park1Department of Plastic and Reconstructive Surgery, Soonchunhyang University Bucheon Hospital, Bucheon, KoreaDepartment of Plastic and Reconstructive Surgery, Soonchunhyang University Bucheon Hospital, Bucheon, KoreaA 3,480 g male neonate showed tachypnea symptom with a serum ionized calcium level of 0.66 mmol/L by routine clinical analysis. He was injected calcium gluconate intravenously through femoral vein catheter to treat the hypocalcemia. On second day after the injection, he started to show erythema in the flank area. The lesion became firm and changed into whitish crust consist of small crystals. Abdominal X-ray and ultrasonography showed the accumulation of calcium deposit in the subcutaneous layer of the lesion. Surgical debridement was performed to remove the crust with calcium deposit and acellular fish skin graft rich in omega-3 (Kerecis) was applied to the defect site for secondary intention of the defect wound. After 2 months, the skin and soft tissue defect were fully covered with healthy normal skin without depression or contracture. This report is a first case of iatrogenic calcinosis cutis without extravasation symptom.http://www.thieme-connect.de/DOI/DOI?10.5999/aps.2020.01942piscine skin acellular matrixkereciscalcinosis cutisinfant, newborn
spellingShingle Kwang Hyeon Ahn
Eun Soo Park
A rare case report of neonatal calcinosis cutis induced by distant and delayed extravasation of intravenous calcium gluconate
Archives of Plastic Surgery
piscine skin acellular matrix
kerecis
calcinosis cutis
infant, newborn
title A rare case report of neonatal calcinosis cutis induced by distant and delayed extravasation of intravenous calcium gluconate
title_full A rare case report of neonatal calcinosis cutis induced by distant and delayed extravasation of intravenous calcium gluconate
title_fullStr A rare case report of neonatal calcinosis cutis induced by distant and delayed extravasation of intravenous calcium gluconate
title_full_unstemmed A rare case report of neonatal calcinosis cutis induced by distant and delayed extravasation of intravenous calcium gluconate
title_short A rare case report of neonatal calcinosis cutis induced by distant and delayed extravasation of intravenous calcium gluconate
title_sort rare case report of neonatal calcinosis cutis induced by distant and delayed extravasation of intravenous calcium gluconate
topic piscine skin acellular matrix
kerecis
calcinosis cutis
infant, newborn
url http://www.thieme-connect.de/DOI/DOI?10.5999/aps.2020.01942
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