Impact of IL-10 and IL-12B single nucleotide polymorphisms on circulating cytokine level in development of Hashimoto's thyroiditis

Impact of IL-10 and IL-12B single nucleotide polymorphisms on circulating cytokine level in development of Hashimoto's thyroiditis

Hashimoto's thyroiditis (HT) is an organ-specific, mainly Th1 autoimmune disorder. New evidence has accumulated for involvement of Treg-produced cytokines. Interleukin (IL)-12 and IL-10 are immunoregulatory cytokines with antagonistic effect on Th differentiation. This study was designed to inv...

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Bibliographic Details
Main Authors: Julieta Gerenova, Irena Manolova, Spaska Stanilova
Format: Article
Language:English
Published: Taylor & Francis Group 2016-07-01
Series:Biotechnology & Biotechnological Equipment
Subjects:
Hashimoto's thyroiditis
IL-10
IL-12
polymorphism
Online Access:http://dx.doi.org/10.1080/13102818.2016.1173522

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