Preventive effect of doxycycline sponge against bisphosphonate-related osteonecrosis of the jaws: an animal study

Preventive effect of doxycycline sponge against bisphosphonate-related osteonecrosis of the jaws: an animal study

The aim of this study is to investigate the effect of doxycycline collagen sponge on bisphosphonate-related osteonecrosis of the jaw (BRONJ) and the level of serum biomarkers as an indicator of osteonecrosis. Twenty-four rats were divided into four groups. Animals in the control group were injected...

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Bibliographic Details
Main Authors: Gonca Duygu Çapar, Melike Sapmaz-Metin, Esma Kütan, Ceyda Ozcakir Tomruk, Gül Merve Yalcin, Nilay Er, Gulnur Kizilay Ozfidan
Format: Article
Language:English
Published: Taylor & Francis Group 2016-07-01
Series:Biotechnology & Biotechnological Equipment
Subjects:
BRONJ
doxycycline
CTx
ALP
TRACP 5b
Online Access:http://dx.doi.org/10.1080/13102818.2016.1174078

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