Influence of Periprostatic Adiposity Measurement Parameters on Preoperative Staging and Grading of Prostate Cancer
Objective To analyze the influence of periprostatic fat on the difference of staging/grading before and after radical retropubic prostatectomy(RRP). Methods A total of 184 patients who underwent RRP were analyzed retrospectively. The different fat measurements were performed on the slices of MRI and...
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Magazine House of Cancer Research on Prevention and Treatment
2018-07-01
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| Series: | Zhongliu Fangzhi Yanjiu |
| Subjects: | |
| Online Access: | http://html.rhhz.net/ZLFZYJ/html/8578.2018.17.1382.htm |
| _version_ | 1828452872839233536 |
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| author | ZHANG Qiang SUN Lijiang ZHANG Guiming QI Jun YANG Zhigang |
| author_facet | ZHANG Qiang SUN Lijiang ZHANG Guiming QI Jun YANG Zhigang |
| author_sort | ZHANG Qiang |
| collection | DOAJ |
| description | Objective To analyze the influence of periprostatic fat on the difference of staging/grading before and after radical retropubic prostatectomy(RRP). Methods A total of 184 patients who underwent RRP were analyzed retrospectively. The different fat measurements were performed on the slices of MRI and compared with the clinical and pathologic factors using SPSS13.0. Results The PFA and Ratio showed a significant difference between the difference group and the no difference one in clinical stage before operation and pathologic stage after operation (P=0.014, P=0.037). A statistical association was revealed between the PFA/Ratio and the difference of grading in pre-/post-RRP (P=0.031, P=0.002). In terms of Gleason score, nothing but "PFA" fat measurement was found to be different between two groups (P=0.017); Logistic regression analysis revealed a statistical association between the PFA/T-zone volume and the difference of grading in pre-/post-RRP (P=0.018, P=0.028). Conclusion The periprostatic adipose has effect on accurate evaluation of preoperative staging and grading of PCa. |
| first_indexed | 2024-12-10T23:59:17Z |
| format | Article |
| id | doaj.art-8d6d00471b73475c9552a4b661eca64c |
| institution | Directory Open Access Journal |
| issn | 1000-8578 1000-8578 |
| language | zho |
| last_indexed | 2024-12-10T23:59:17Z |
| publishDate | 2018-07-01 |
| publisher | Magazine House of Cancer Research on Prevention and Treatment |
| record_format | Article |
| series | Zhongliu Fangzhi Yanjiu |
| spelling | doaj.art-8d6d00471b73475c9552a4b661eca64c2022-12-22T01:28:31ZzhoMagazine House of Cancer Research on Prevention and TreatmentZhongliu Fangzhi Yanjiu1000-85781000-85782018-07-0145748849110.3971/j.issn.1000-8578.2018.17.13828578.2018.17.1382Influence of Periprostatic Adiposity Measurement Parameters on Preoperative Staging and Grading of Prostate CancerZHANG Qiang0SUN Lijiang1ZHANG Guiming2QI Jun3YANG Zhigang4Department of Urology, Baotou Central Hospital, Baotou 014040, ChinaDepartment of Urology, The Affiliated Hospital of Qingdao University, Qingdao 266003, ChinaDepartment of Urology, The Affiliated Hospital of Qingdao University, Qingdao 266003, ChinaDepartmentof Urology, Xinhua Hospital Affiliated to Shanghai Jiaotong University School of Medcine, Shanghai 200092, ChinaDepartment of Urology, Baotou Central Hospital, Baotou 014040, ChinaObjective To analyze the influence of periprostatic fat on the difference of staging/grading before and after radical retropubic prostatectomy(RRP). Methods A total of 184 patients who underwent RRP were analyzed retrospectively. The different fat measurements were performed on the slices of MRI and compared with the clinical and pathologic factors using SPSS13.0. Results The PFA and Ratio showed a significant difference between the difference group and the no difference one in clinical stage before operation and pathologic stage after operation (P=0.014, P=0.037). A statistical association was revealed between the PFA/Ratio and the difference of grading in pre-/post-RRP (P=0.031, P=0.002). In terms of Gleason score, nothing but "PFA" fat measurement was found to be different between two groups (P=0.017); Logistic regression analysis revealed a statistical association between the PFA/T-zone volume and the difference of grading in pre-/post-RRP (P=0.018, P=0.028). Conclusion The periprostatic adipose has effect on accurate evaluation of preoperative staging and grading of PCa.http://html.rhhz.net/ZLFZYJ/html/8578.2018.17.1382.htmprostate cancerstaginggleason scoreperiprostatic adiposity |
| spellingShingle | ZHANG Qiang SUN Lijiang ZHANG Guiming QI Jun YANG Zhigang Influence of Periprostatic Adiposity Measurement Parameters on Preoperative Staging and Grading of Prostate Cancer Zhongliu Fangzhi Yanjiu prostate cancer staging gleason score periprostatic adiposity |
| title | Influence of Periprostatic Adiposity Measurement Parameters on Preoperative Staging and Grading of Prostate Cancer |
| title_full | Influence of Periprostatic Adiposity Measurement Parameters on Preoperative Staging and Grading of Prostate Cancer |
| title_fullStr | Influence of Periprostatic Adiposity Measurement Parameters on Preoperative Staging and Grading of Prostate Cancer |
| title_full_unstemmed | Influence of Periprostatic Adiposity Measurement Parameters on Preoperative Staging and Grading of Prostate Cancer |
| title_short | Influence of Periprostatic Adiposity Measurement Parameters on Preoperative Staging and Grading of Prostate Cancer |
| title_sort | influence of periprostatic adiposity measurement parameters on preoperative staging and grading of prostate cancer |
| topic | prostate cancer staging gleason score periprostatic adiposity |
| url | http://html.rhhz.net/ZLFZYJ/html/8578.2018.17.1382.htm |
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