Discovery of nonnucleoside inhibitors of polymerase from infectious pancreatic necrosis virus (IPNV)

Discovery of nonnucleoside inhibitors of polymerase from infectious pancreatic necrosis virus (IPNV)

Melissa Bello-Pérez,1 Alberto Falcó,1 Vicente Galiano,2 Julio Coll,3 Luis Perez,1 José Antonio Encinar1 1Molecular and Cell Biology Institute (IBMC), Miguel Hernández University (UMH), Elche, Spain; 2Department of Physics and Computer Architecture, Miguel...

Full description

Bibliographic Details
Main Authors:	Bello-Pérez M, Falco A, Galiano V, Coll J, Perez L, Encinar JA
Format:	Article
Language:	English
Published:	Dove Medical Press 2018-07-01
Series:	Drug Design, Development and Therapy
Subjects:	IPNV HCV antiviral drugs non-nucleoside inhibitors RNA-dependent RNA polymerase molecular docking
Online Access:	https://www.dovepress.com/discovery-of-nonnucleoside-inhibitors-of-polymerase-from-infectious-pa-peer-reviewed-article-DDDT

Similar Items

The Infectious Pancreatic Necrosis Virus (IPNV) and its Virulence Determinants: What is Known and What Should be Known
by: Carlos P. Dopazo
Published: (2020-02-01)

Diagnosis of infectious pancreatic necrosis virus (IPNV): Review
by: M. Nazarenko, et al.
Published: (2022-03-01)

Evaluation of the Antiviral Activity against Infectious Pancreatic Necrosis Virus (IPNV) of a Copper (I) Homoleptic Complex with a Coumarin as Ligand
by: Daniela Gutiérrez, et al.
Published: (2021-12-01)

Differential Transcriptomic Response of Rainbow Trout to Infection with Two Strains of IPNV
by: David Tapia, et al.
Published: (2021-12-01)

Isolation of a New Infectious Pancreatic Necrosis Virus (IPNV) Variant from a Fish Farm in Scotland
by: Jessica Benkaroun, et al.
Published: (2021-02-01)

Infectious pancreatic necrosis virus (IPNV) from salmonid fish enters, but does not replicate in, mammalian cells
by: Ørpetveit Irene, et al.
Published: (2012-10-01)

The Paramyxovirus Polymerase Complex as a Target for Next-Generation Anti-Paramyxovirus Therapeutics
by: Richard K Plemper, et al.
Published: (2015-05-01)

Identification of a New Infectious Pancreatic Necrosis Virus (IPNV) Variant in Atlantic Salmon (Salmo salar L.) that can Cause High Mortality Even in Genetically Resistant Fish
by: Borghild Hillestad, et al.
Published: (2021-11-01)

Antiviral Activity of Crude Polysaccharide Derived from Seaweed against IHNV and IPNV In Vitro
by: Guangming Ren, et al.
Published: (2022-09-01)

Effect of temperature on the expression of IFN-1 (α), STAT-1 and Mx-1 genes in Oncorhynchus mykiss (Salmoniformes: Salmonidae) exposed with the virus of the infectious pancreatic necrosis (IPNV)
by: Donald Arguedas Cortés, et al.
Published: (2015-06-01)

miRNAs Predicted to Regulate Host Anti-viral Gene Pathways in IPNV-Challenged Atlantic Salmon Fry Are Affected by Viral Load, and Associated With the Major IPN Resistance QTL Genotypes in Late Infection
by: Nardos Tesfaye Woldemariam, et al.
Published: (2020-09-01)

IPNV Antigen Uptake and Distribution in Atlantic Salmon Following Oral Administration
by: Lihan Chen, et al.
Published: (2015-05-01)

IPNV with high and low virulence: host immune responses and viral mutations during infection
by: Skjesol Astrid, et al.
Published: (2011-08-01)

Looking for inhibitors of the dengue virus NS5 RNA-dependent RNA-polymerase using a molecular docking approach
by: Galiano V, et al.
Published: (2016-10-01)

Relationship between apoptosis and the BH2 domain sequence of the VP5 peptide of infectious pancreatic necrosis virus
by: Cesar Ortega S, et al.
Published: (2014-01-01)

Relationship between apoptosis and the BH2 domain sequence of the VP5 peptide of infectious pancreatic necrosis virus
by: Cesar Ortega S., et al.
Published: (2014-03-01)

Quantitative Flow Cytometry to Measure Viral Production Using Infectious Pancreatic Necrosis Virus as a Model: A Preliminary Study
by: Diego Vázquez, et al.
Published: (2018-09-01)

Characterization of a Novel Infectious Pancreatic Necrosis Virus (IPNV) from Genogroup 6 Identified in Sea Trout (<i>Salmo trutta</i>) from Lake Vänern, Sweden
by: B. David Persson, et al.
Published: (2023-01-01)

Dynamic Distribution of Infectious Pancreatic Necrosis Virus (IPNV) Strains of Genogroups 1, 5, and 7 after Intraperitoneal Administration in Rainbow Trout (<i>Oncorhynchus mykiss</i>)
by: Yizhi Shao, et al.
Published: (2022-11-01)

Inter-laboratory ring trial to evaluate real-time reverse transcription polymerase chain reaction methods used for detection of infectious pancreatic necrosis virus in Chile
by: David Tapia, et al.
Published: (2017-07-01)

Potent Anti‐HIV Activity of Alkyl‐Modified DiPPro‐Nucleotides
by: Xiao Jia, et al.
Published: (2024-04-01)

Inhibitors of the Hepatitis C Virus Polymerase; Mode of Action and Resistance
by: Auda A. Eltahla, et al.
Published: (2015-09-01)

Drug Discovery of Nucleos(t)ide Antiviral Agents: Dedicated to Prof. Dr. Erik De Clercq on Occasion of His 80th Birthday
by: Guangdi Li, et al.
Published: (2021-02-01)

Purification and Biochemical Characterisation of Rabbit Calicivirus RNA-Dependent RNA Polymerases and Identification of Non-Nucleoside Inhibitors
by: Nadya Urakova, et al.
Published: (2016-04-01)

Fludarabine, a Potential DNA-Dependent RNA Polymerase Inhibitor, as a Prospective Drug against Monkeypox Virus: A Computational Approach
by: Hisham N. Altayb
Published: (2022-09-01)

Isolation of a New Infectious Pancreatic Necrosis Virus (IPNV) Variant from Genetically Resistant Farmed Atlantic Salmon (<i>Salmo salar</i>) during 2021–2022
by: Marcos Godoy, et al.
Published: (2022-11-01)

Antiviral Activity of N<sub>1</sub>,N<sub>3</sub>-Disubstituted Uracil Derivatives against SARS-CoV-2 Variants of Concern
by: Andrei E. Siniavin, et al.
Published: (2022-09-01)

Lactococcus lactis Expressing Type I Interferon From Atlantic Salmon Enhances the Innate Antiviral Immune Response In Vivo and In Vitro
by: Carlos Muñoz, et al.
Published: (2021-08-01)

PKR Activation Favors Infectious Pancreatic Necrosis Virus Replication in Infected Cells
by: Amr A.A. Gamil, et al.
Published: (2016-06-01)

The Adenosine Analogue NITD008 has Potent Antiviral Activity against Human and Animal Caliciviruses
by: Daniel Enosi Tuipulotu, et al.
Published: (2019-05-01)

Raltegravir, Indinavir, Tipranavir, Dolutegravir, and Etravirine against main protease and RNA-dependent RNA polymerase of SARS-CoV-2: A molecular docking and drug repurposing approach
by: Purushothaman Indu, et al.
Published: (2020-12-01)

Nucleotide Loading Modes of Human RNA Polymerase II as Deciphered by Molecular Simulations
by: Nicolas E. J. Génin, et al.
Published: (2020-09-01)

Current understanding of nucleoside analogs inhibiting the SARS-CoV-2 RNA-dependent RNA polymerase
by: Tiantian Xu, et al.
Published: (2023-01-01)

Cytidine nucleoside analog is an effective antiviral drug against Trichomonasvirus
by: Ravi Kumar Narayanasamy, et al.
Published: (2022-04-01)

Progression of Antiviral Agents Targeting Viral Polymerases
by: Siqi Peng, et al.
Published: (2022-10-01)

Efficient elimination of RNA mycoviruses in aspergillus species using RdRp-inhibitors ribavirin and 2’-C-methylribonucleoside derivatives
by: Ayano Ikeda, et al.
Published: (2022-10-01)

Recent Advances in Molecular Mechanisms of Nucleoside Antivirals
by: Polina N. Kamzeeva, et al.
Published: (2023-08-01)

Identifying Different Mutation Sites Leading to Resistance to the Direct-Acting Antiviral (DAA) Sofosbuvir in Hepatitis C Virus Patients from Egypt
by: Aly Atef Shoun, et al.
Published: (2022-03-01)

Multisubunit RNA Polymerases of Jumbo Bacteriophages
by: Maria L. Sokolova, et al.
Published: (2020-09-01)

Identifying Small-Molecule Inhibitors of SARS-CoV-2 RNA-Dependent RNA Polymerase by Establishing a Fluorometric Assay
by: Xiaoming Bai, et al.
Published: (2022-04-01)