Axin2+ endometrial stem cells: the source of endometrial regeneration and cancer
Menstruation is one of the basic but poorly understood life processes in primates during which females shed inner uterine lining every month only to be completely regenerated back within a week. The definitive evidence for the existence and/or identity of stem cells responsible for this process has...
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
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Taylor & Francis Group
2020-05-01
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| Series: | Molecular & Cellular Oncology |
| Subjects: | |
| Online Access: | http://dx.doi.org/10.1080/23723556.2020.1729681 |
| _version_ | 1797677154814656512 |
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| author | Shafiq M. Syed Pradeep S. Tanwar |
| author_facet | Shafiq M. Syed Pradeep S. Tanwar |
| author_sort | Shafiq M. Syed |
| collection | DOAJ |
| description | Menstruation is one of the basic but poorly understood life processes in primates during which females shed inner uterine lining every month only to be completely regenerated back within a week. The definitive evidence for the existence and/or identity of stem cells responsible for this process has remained elusive for more than six decades now. Recently, we reported Axin2, a classical Wnt reporter gene, as a marker for endometrial stem cells that also serve as the cells of origin for endometrial cancer. |
| first_indexed | 2024-03-11T22:40:55Z |
| format | Article |
| id | doaj.art-8d7b79c081a24ae4a258ec67f9b0286f |
| institution | Directory Open Access Journal |
| issn | 2372-3556 |
| language | English |
| last_indexed | 2024-03-11T22:40:55Z |
| publishDate | 2020-05-01 |
| publisher | Taylor & Francis Group |
| record_format | Article |
| series | Molecular & Cellular Oncology |
| spelling | doaj.art-8d7b79c081a24ae4a258ec67f9b0286f2023-09-22T09:11:01ZengTaylor & Francis GroupMolecular & Cellular Oncology2372-35562020-05-017310.1080/23723556.2020.17296811729681Axin2+ endometrial stem cells: the source of endometrial regeneration and cancerShafiq M. Syed0Pradeep S. Tanwar1University of NewcastleUniversity of NewcastleMenstruation is one of the basic but poorly understood life processes in primates during which females shed inner uterine lining every month only to be completely regenerated back within a week. The definitive evidence for the existence and/or identity of stem cells responsible for this process has remained elusive for more than six decades now. Recently, we reported Axin2, a classical Wnt reporter gene, as a marker for endometrial stem cells that also serve as the cells of origin for endometrial cancer.http://dx.doi.org/10.1080/23723556.2020.1729681endometrial stem cellscancerregenerationaxin2wnt signaling |
| spellingShingle | Shafiq M. Syed Pradeep S. Tanwar Axin2+ endometrial stem cells: the source of endometrial regeneration and cancer Molecular & Cellular Oncology endometrial stem cells cancer regeneration axin2 wnt signaling |
| title | Axin2+ endometrial stem cells: the source of endometrial regeneration and cancer |
| title_full | Axin2+ endometrial stem cells: the source of endometrial regeneration and cancer |
| title_fullStr | Axin2+ endometrial stem cells: the source of endometrial regeneration and cancer |
| title_full_unstemmed | Axin2+ endometrial stem cells: the source of endometrial regeneration and cancer |
| title_short | Axin2+ endometrial stem cells: the source of endometrial regeneration and cancer |
| title_sort | axin2 endometrial stem cells the source of endometrial regeneration and cancer |
| topic | endometrial stem cells cancer regeneration axin2 wnt signaling |
| url | http://dx.doi.org/10.1080/23723556.2020.1729681 |
| work_keys_str_mv | AT shafiqmsyed axin2endometrialstemcellsthesourceofendometrialregenerationandcancer AT pradeepstanwar axin2endometrialstemcellsthesourceofendometrialregenerationandcancer |