Night shift work and cardiovascular diseases among employees in Germany: five-year follow-up of the Gutenberg Health Study
OBJECTIVE: This study aimed to determine if there is an increased risk of incident cardiovascular diseases (CVD) resulting from cumulative night shift work in the German population-based Gutenberg Health Study (GHS). METHODS: We examined working participants of the GHS at baseline and after five yea...
| Main Authors: | , , , , , , , , , , , , , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Nordic Association of Occupational Safety and Health (NOROSH)
2024-04-01
|
| Series: | Scandinavian Journal of Work, Environment & Health |
| Subjects: | |
| Online Access: |
https://www.sjweh.fi/article/4139
|
| _version_ | 1797242624794427392 |
|---|---|
| author | Sylvia Jankowiak Karin Rossnagel Juliane Bauer Andreas Schulz Falk Liebers Ute Latza Karla Romero Starke Andreas Seidler Matthias Nübling Merle Riechmann-Wolf Stephan Letzel Philipp Wild Natalie Arnold Manfred Beutel Norbert Pfeiffer Karl Lackner Thomas Münzel Alicia Schulze Janice Hegewald |
| author_facet | Sylvia Jankowiak Karin Rossnagel Juliane Bauer Andreas Schulz Falk Liebers Ute Latza Karla Romero Starke Andreas Seidler Matthias Nübling Merle Riechmann-Wolf Stephan Letzel Philipp Wild Natalie Arnold Manfred Beutel Norbert Pfeiffer Karl Lackner Thomas Münzel Alicia Schulze Janice Hegewald |
| author_sort | Sylvia Jankowiak |
| collection | DOAJ |
| description | OBJECTIVE: This study aimed to determine if there is an increased risk of incident cardiovascular diseases (CVD) resulting from cumulative night shift work in the German population-based Gutenberg Health Study (GHS). METHODS: We examined working participants of the GHS at baseline and after five years. Cumulative night shift work in the 10 years before baseline was assessed and categorized as low (1–220 nights ≙ up to 1 year), middle (221–660 nights ≙ 1–3 years), and high (>660 nights ≙ more than 3 years) night shift exposure. Hazard ratios (HR) were estimated for incident “quality-assured CVD events” using Cox proportional hazard models. RESULTS: At baseline, 1092 of 8167 working participants performed night shift work. During the follow-up, 202 incident cardiovascular events occurred. The crude incidence rates for CVD per 1000 person-years were 6.88 [95% confidence interval (CI) 4.80–9.55] for night shift workers and 5.19 (95% CI 4.44–6.04) for day workers. Cumulative incidence curves showed a higher cumulative incidence in workers exposed to night shift work compared to day workers after five years. The adjusted HR for incident CVD events were 1.26 (95% CI 0.68–2.33), 1.37 (95% CI 0.74–2.53) and 1.19 (95% CI 0.67–2.12) for employees in the low, middle and high night shift categories compared to employees without night shift work, respectively. CONCLUSIONS: The observed tendencies indicate that night shift work might be negatively associated with cardiovascular health. We expect the continued follow-up will clarify the long-term impact of night shift work. |
| first_indexed | 2024-04-24T18:42:11Z |
| format | Article |
| id | doaj.art-8d7c4ca890774f5f9a4f3f18bfd89092 |
| institution | Directory Open Access Journal |
| issn | 0355-3140 1795-990X |
| language | English |
| last_indexed | 2024-04-24T18:42:11Z |
| publishDate | 2024-04-01 |
| publisher | Nordic Association of Occupational Safety and Health (NOROSH) |
| record_format | Article |
| series | Scandinavian Journal of Work, Environment & Health |
| spelling | doaj.art-8d7c4ca890774f5f9a4f3f18bfd890922024-03-27T11:01:37ZengNordic Association of Occupational Safety and Health (NOROSH)Scandinavian Journal of Work, Environment & Health0355-31401795-990X2024-04-0150314215110.5271/sjweh.41394139Night shift work and cardiovascular diseases among employees in Germany: five-year follow-up of the Gutenberg Health StudySylvia JankowiakKarin RossnagelJuliane BauerAndreas SchulzFalk LiebersUte LatzaKarla Romero StarkeAndreas SeidlerMatthias NüblingMerle Riechmann-WolfStephan LetzelPhilipp WildNatalie ArnoldManfred BeutelNorbert PfeifferKarl LacknerThomas MünzelAlicia SchulzeJanice HegewaldOBJECTIVE: This study aimed to determine if there is an increased risk of incident cardiovascular diseases (CVD) resulting from cumulative night shift work in the German population-based Gutenberg Health Study (GHS). METHODS: We examined working participants of the GHS at baseline and after five years. Cumulative night shift work in the 10 years before baseline was assessed and categorized as low (1–220 nights ≙ up to 1 year), middle (221–660 nights ≙ 1–3 years), and high (>660 nights ≙ more than 3 years) night shift exposure. Hazard ratios (HR) were estimated for incident “quality-assured CVD events” using Cox proportional hazard models. RESULTS: At baseline, 1092 of 8167 working participants performed night shift work. During the follow-up, 202 incident cardiovascular events occurred. The crude incidence rates for CVD per 1000 person-years were 6.88 [95% confidence interval (CI) 4.80–9.55] for night shift workers and 5.19 (95% CI 4.44–6.04) for day workers. Cumulative incidence curves showed a higher cumulative incidence in workers exposed to night shift work compared to day workers after five years. The adjusted HR for incident CVD events were 1.26 (95% CI 0.68–2.33), 1.37 (95% CI 0.74–2.53) and 1.19 (95% CI 0.67–2.12) for employees in the low, middle and high night shift categories compared to employees without night shift work, respectively. CONCLUSIONS: The observed tendencies indicate that night shift work might be negatively associated with cardiovascular health. We expect the continued follow-up will clarify the long-term impact of night shift work. https://www.sjweh.fi/article/4139 occupationcardiovascular diseaselongitudinal studyincidencecohort studyshift workworkplaceemployeenight shiftgermanycvdrhineland-palatinatepopulation-basedghsgutenberg health study |
| spellingShingle | Sylvia Jankowiak Karin Rossnagel Juliane Bauer Andreas Schulz Falk Liebers Ute Latza Karla Romero Starke Andreas Seidler Matthias Nübling Merle Riechmann-Wolf Stephan Letzel Philipp Wild Natalie Arnold Manfred Beutel Norbert Pfeiffer Karl Lackner Thomas Münzel Alicia Schulze Janice Hegewald Night shift work and cardiovascular diseases among employees in Germany: five-year follow-up of the Gutenberg Health Study Scandinavian Journal of Work, Environment & Health occupation cardiovascular disease longitudinal study incidence cohort study shift work workplace employee night shift germany cvd rhineland-palatinate population-based ghs gutenberg health study |
| title | Night shift work and cardiovascular diseases among employees in Germany: five-year follow-up of the Gutenberg Health Study |
| title_full | Night shift work and cardiovascular diseases among employees in Germany: five-year follow-up of the Gutenberg Health Study |
| title_fullStr | Night shift work and cardiovascular diseases among employees in Germany: five-year follow-up of the Gutenberg Health Study |
| title_full_unstemmed | Night shift work and cardiovascular diseases among employees in Germany: five-year follow-up of the Gutenberg Health Study |
| title_short | Night shift work and cardiovascular diseases among employees in Germany: five-year follow-up of the Gutenberg Health Study |
| title_sort | night shift work and cardiovascular diseases among employees in germany five year follow up of the gutenberg health study |
| topic | occupation cardiovascular disease longitudinal study incidence cohort study shift work workplace employee night shift germany cvd rhineland-palatinate population-based ghs gutenberg health study |
| url |
https://www.sjweh.fi/article/4139
|
| work_keys_str_mv | AT sylviajankowiak nightshiftworkandcardiovasculardiseasesamongemployeesingermanyfiveyearfollowupofthegutenberghealthstudy AT karinrossnagel nightshiftworkandcardiovasculardiseasesamongemployeesingermanyfiveyearfollowupofthegutenberghealthstudy AT julianebauer nightshiftworkandcardiovasculardiseasesamongemployeesingermanyfiveyearfollowupofthegutenberghealthstudy AT andreasschulz nightshiftworkandcardiovasculardiseasesamongemployeesingermanyfiveyearfollowupofthegutenberghealthstudy AT falkliebers nightshiftworkandcardiovasculardiseasesamongemployeesingermanyfiveyearfollowupofthegutenberghealthstudy AT utelatza nightshiftworkandcardiovasculardiseasesamongemployeesingermanyfiveyearfollowupofthegutenberghealthstudy AT karlaromerostarke nightshiftworkandcardiovasculardiseasesamongemployeesingermanyfiveyearfollowupofthegutenberghealthstudy AT andreasseidler nightshiftworkandcardiovasculardiseasesamongemployeesingermanyfiveyearfollowupofthegutenberghealthstudy AT matthiasnubling nightshiftworkandcardiovasculardiseasesamongemployeesingermanyfiveyearfollowupofthegutenberghealthstudy AT merleriechmannwolf nightshiftworkandcardiovasculardiseasesamongemployeesingermanyfiveyearfollowupofthegutenberghealthstudy AT stephanletzel nightshiftworkandcardiovasculardiseasesamongemployeesingermanyfiveyearfollowupofthegutenberghealthstudy AT philippwild nightshiftworkandcardiovasculardiseasesamongemployeesingermanyfiveyearfollowupofthegutenberghealthstudy AT nataliearnold nightshiftworkandcardiovasculardiseasesamongemployeesingermanyfiveyearfollowupofthegutenberghealthstudy AT manfredbeutel nightshiftworkandcardiovasculardiseasesamongemployeesingermanyfiveyearfollowupofthegutenberghealthstudy AT norbertpfeiffer nightshiftworkandcardiovasculardiseasesamongemployeesingermanyfiveyearfollowupofthegutenberghealthstudy AT karllackner nightshiftworkandcardiovasculardiseasesamongemployeesingermanyfiveyearfollowupofthegutenberghealthstudy AT thomasmunzel nightshiftworkandcardiovasculardiseasesamongemployeesingermanyfiveyearfollowupofthegutenberghealthstudy AT aliciaschulze nightshiftworkandcardiovasculardiseasesamongemployeesingermanyfiveyearfollowupofthegutenberghealthstudy AT janicehegewald nightshiftworkandcardiovasculardiseasesamongemployeesingermanyfiveyearfollowupofthegutenberghealthstudy |