SAS-PRP Study: A Real-Life Satisfaction Assessment in Patients with Cartilage Lesions of the Knee Treated by Platelet-Rich Plasma
Platelet-rich plasma (PRP) is a rising therapy treating locomotor system lesions such as knee osteoarthritis. The objective of this study was to evaluate patients’ satisfaction 6 to 12 months after a PRP injection for cartilage lesions of their knee under real-life conditions. Patients’ satisfaction...
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MDPI AG
2023-11-01
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author | Romain Verron Lucie Zhang Hélène Bisseriex Ronan Grimandi Alix Verrando Claire Verdaguer Marie Thomas Julia Facione Leo Borrini |
author_facet | Romain Verron Lucie Zhang Hélène Bisseriex Ronan Grimandi Alix Verrando Claire Verdaguer Marie Thomas Julia Facione Leo Borrini |
author_sort | Romain Verron |
collection | DOAJ |
description | Platelet-rich plasma (PRP) is a rising therapy treating locomotor system lesions such as knee osteoarthritis. The objective of this study was to evaluate patients’ satisfaction 6 to 12 months after a PRP injection for cartilage lesions of their knee under real-life conditions. Patients’ satisfaction was assessed by a specific questionnaire named SATMED-Q©, which explores six different dimensions of a given treatment. In addition, pain and function were assessed thanks to VAS pain, WOMAC, and IKDC scores. Responders were identified through the OMERACT-OARSI criteria. We observed excellent satisfaction after a PRP injection with a SATMED-Q© score of 80.81% 6 to 12 months after the procedure. Even when there was no significant improvement in pain and function scores, 52% of the evaluated population fulfilled the OMERACT-OARSI criteria and were considered responders. According to the sub-group analysis, patients with less osteoarthritis damage (i.e., Kellgren–Lawrence grades 1–2) and older study subjects (i.e., >40 years old) with focal chondropathy had benefited most from their PRP injection. Thus, platelet-rich plasma seems to be a well-tolerated and efficient therapy for cartilage lesions of the knee. |
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institution | Directory Open Access Journal |
issn | 2306-5354 |
language | English |
last_indexed | 2024-03-09T17:00:45Z |
publishDate | 2023-11-01 |
publisher | MDPI AG |
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series | Bioengineering |
spelling | doaj.art-8d7f75850bf94d3a8ad2b6e3fe6956a32023-11-24T14:29:47ZengMDPI AGBioengineering2306-53542023-11-011011127610.3390/bioengineering10111276SAS-PRP Study: A Real-Life Satisfaction Assessment in Patients with Cartilage Lesions of the Knee Treated by Platelet-Rich PlasmaRomain Verron0Lucie Zhang1Hélène Bisseriex2Ronan Grimandi3Alix Verrando4Claire Verdaguer5Marie Thomas6Julia Facione7Leo Borrini8Physical and Rehabilitation Department, HIA Percy, 92140 Clamart, FrancePneumology Department, HIA Clermont-Tonnerre, 29200 Brest, FrancePhysical and Rehabilitation Department, HIA Clermont-Tonnerre, 29200 Brest, FrancePhysical and Rehabilitation Department, HIA Clermont-Tonnerre, 29200 Brest, FrancePhysical and Rehabilitation Department, HIA Percy, 92140 Clamart, FrancePhysical and Rehabilitation Department, HIA Percy, 92140 Clamart, FrancePhysical and Rehabilitation Department, HIA Percy, 92140 Clamart, FrancePhysical and Rehabilitation Department, HIA Percy, 92140 Clamart, FrancePhysical and Rehabilitation Department, HIA Percy, 92140 Clamart, FrancePlatelet-rich plasma (PRP) is a rising therapy treating locomotor system lesions such as knee osteoarthritis. The objective of this study was to evaluate patients’ satisfaction 6 to 12 months after a PRP injection for cartilage lesions of their knee under real-life conditions. Patients’ satisfaction was assessed by a specific questionnaire named SATMED-Q©, which explores six different dimensions of a given treatment. In addition, pain and function were assessed thanks to VAS pain, WOMAC, and IKDC scores. Responders were identified through the OMERACT-OARSI criteria. We observed excellent satisfaction after a PRP injection with a SATMED-Q© score of 80.81% 6 to 12 months after the procedure. Even when there was no significant improvement in pain and function scores, 52% of the evaluated population fulfilled the OMERACT-OARSI criteria and were considered responders. According to the sub-group analysis, patients with less osteoarthritis damage (i.e., Kellgren–Lawrence grades 1–2) and older study subjects (i.e., >40 years old) with focal chondropathy had benefited most from their PRP injection. Thus, platelet-rich plasma seems to be a well-tolerated and efficient therapy for cartilage lesions of the knee.https://www.mdpi.com/2306-5354/10/11/1276platelet-rich plasmaosteoarthritiskneecartilageintra-articular injectionSATMED-Q© |
spellingShingle | Romain Verron Lucie Zhang Hélène Bisseriex Ronan Grimandi Alix Verrando Claire Verdaguer Marie Thomas Julia Facione Leo Borrini SAS-PRP Study: A Real-Life Satisfaction Assessment in Patients with Cartilage Lesions of the Knee Treated by Platelet-Rich Plasma Bioengineering platelet-rich plasma osteoarthritis knee cartilage intra-articular injection SATMED-Q© |
title | SAS-PRP Study: A Real-Life Satisfaction Assessment in Patients with Cartilage Lesions of the Knee Treated by Platelet-Rich Plasma |
title_full | SAS-PRP Study: A Real-Life Satisfaction Assessment in Patients with Cartilage Lesions of the Knee Treated by Platelet-Rich Plasma |
title_fullStr | SAS-PRP Study: A Real-Life Satisfaction Assessment in Patients with Cartilage Lesions of the Knee Treated by Platelet-Rich Plasma |
title_full_unstemmed | SAS-PRP Study: A Real-Life Satisfaction Assessment in Patients with Cartilage Lesions of the Knee Treated by Platelet-Rich Plasma |
title_short | SAS-PRP Study: A Real-Life Satisfaction Assessment in Patients with Cartilage Lesions of the Knee Treated by Platelet-Rich Plasma |
title_sort | sas prp study a real life satisfaction assessment in patients with cartilage lesions of the knee treated by platelet rich plasma |
topic | platelet-rich plasma osteoarthritis knee cartilage intra-articular injection SATMED-Q© |
url | https://www.mdpi.com/2306-5354/10/11/1276 |
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