SAS-PRP Study: A Real-Life Satisfaction Assessment in Patients with Cartilage Lesions of the Knee Treated by Platelet-Rich Plasma

Platelet-rich plasma (PRP) is a rising therapy treating locomotor system lesions such as knee osteoarthritis. The objective of this study was to evaluate patients’ satisfaction 6 to 12 months after a PRP injection for cartilage lesions of their knee under real-life conditions. Patients’ satisfaction...

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Main Authors: Romain Verron, Lucie Zhang, Hélène Bisseriex, Ronan Grimandi, Alix Verrando, Claire Verdaguer, Marie Thomas, Julia Facione, Leo Borrini
Format: Article
Language:English
Published: MDPI AG 2023-11-01
Series:Bioengineering
Subjects:
Online Access:https://www.mdpi.com/2306-5354/10/11/1276
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author Romain Verron
Lucie Zhang
Hélène Bisseriex
Ronan Grimandi
Alix Verrando
Claire Verdaguer
Marie Thomas
Julia Facione
Leo Borrini
author_facet Romain Verron
Lucie Zhang
Hélène Bisseriex
Ronan Grimandi
Alix Verrando
Claire Verdaguer
Marie Thomas
Julia Facione
Leo Borrini
author_sort Romain Verron
collection DOAJ
description Platelet-rich plasma (PRP) is a rising therapy treating locomotor system lesions such as knee osteoarthritis. The objective of this study was to evaluate patients’ satisfaction 6 to 12 months after a PRP injection for cartilage lesions of their knee under real-life conditions. Patients’ satisfaction was assessed by a specific questionnaire named SATMED-Q©, which explores six different dimensions of a given treatment. In addition, pain and function were assessed thanks to VAS pain, WOMAC, and IKDC scores. Responders were identified through the OMERACT-OARSI criteria. We observed excellent satisfaction after a PRP injection with a SATMED-Q© score of 80.81% 6 to 12 months after the procedure. Even when there was no significant improvement in pain and function scores, 52% of the evaluated population fulfilled the OMERACT-OARSI criteria and were considered responders. According to the sub-group analysis, patients with less osteoarthritis damage (i.e., Kellgren–Lawrence grades 1–2) and older study subjects (i.e., >40 years old) with focal chondropathy had benefited most from their PRP injection. Thus, platelet-rich plasma seems to be a well-tolerated and efficient therapy for cartilage lesions of the knee.
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spelling doaj.art-8d7f75850bf94d3a8ad2b6e3fe6956a32023-11-24T14:29:47ZengMDPI AGBioengineering2306-53542023-11-011011127610.3390/bioengineering10111276SAS-PRP Study: A Real-Life Satisfaction Assessment in Patients with Cartilage Lesions of the Knee Treated by Platelet-Rich PlasmaRomain Verron0Lucie Zhang1Hélène Bisseriex2Ronan Grimandi3Alix Verrando4Claire Verdaguer5Marie Thomas6Julia Facione7Leo Borrini8Physical and Rehabilitation Department, HIA Percy, 92140 Clamart, FrancePneumology Department, HIA Clermont-Tonnerre, 29200 Brest, FrancePhysical and Rehabilitation Department, HIA Clermont-Tonnerre, 29200 Brest, FrancePhysical and Rehabilitation Department, HIA Clermont-Tonnerre, 29200 Brest, FrancePhysical and Rehabilitation Department, HIA Percy, 92140 Clamart, FrancePhysical and Rehabilitation Department, HIA Percy, 92140 Clamart, FrancePhysical and Rehabilitation Department, HIA Percy, 92140 Clamart, FrancePhysical and Rehabilitation Department, HIA Percy, 92140 Clamart, FrancePhysical and Rehabilitation Department, HIA Percy, 92140 Clamart, FrancePlatelet-rich plasma (PRP) is a rising therapy treating locomotor system lesions such as knee osteoarthritis. The objective of this study was to evaluate patients’ satisfaction 6 to 12 months after a PRP injection for cartilage lesions of their knee under real-life conditions. Patients’ satisfaction was assessed by a specific questionnaire named SATMED-Q©, which explores six different dimensions of a given treatment. In addition, pain and function were assessed thanks to VAS pain, WOMAC, and IKDC scores. Responders were identified through the OMERACT-OARSI criteria. We observed excellent satisfaction after a PRP injection with a SATMED-Q© score of 80.81% 6 to 12 months after the procedure. Even when there was no significant improvement in pain and function scores, 52% of the evaluated population fulfilled the OMERACT-OARSI criteria and were considered responders. According to the sub-group analysis, patients with less osteoarthritis damage (i.e., Kellgren–Lawrence grades 1–2) and older study subjects (i.e., >40 years old) with focal chondropathy had benefited most from their PRP injection. Thus, platelet-rich plasma seems to be a well-tolerated and efficient therapy for cartilage lesions of the knee.https://www.mdpi.com/2306-5354/10/11/1276platelet-rich plasmaosteoarthritiskneecartilageintra-articular injectionSATMED-Q©
spellingShingle Romain Verron
Lucie Zhang
Hélène Bisseriex
Ronan Grimandi
Alix Verrando
Claire Verdaguer
Marie Thomas
Julia Facione
Leo Borrini
SAS-PRP Study: A Real-Life Satisfaction Assessment in Patients with Cartilage Lesions of the Knee Treated by Platelet-Rich Plasma
Bioengineering
platelet-rich plasma
osteoarthritis
knee
cartilage
intra-articular injection
SATMED-Q©
title SAS-PRP Study: A Real-Life Satisfaction Assessment in Patients with Cartilage Lesions of the Knee Treated by Platelet-Rich Plasma
title_full SAS-PRP Study: A Real-Life Satisfaction Assessment in Patients with Cartilage Lesions of the Knee Treated by Platelet-Rich Plasma
title_fullStr SAS-PRP Study: A Real-Life Satisfaction Assessment in Patients with Cartilage Lesions of the Knee Treated by Platelet-Rich Plasma
title_full_unstemmed SAS-PRP Study: A Real-Life Satisfaction Assessment in Patients with Cartilage Lesions of the Knee Treated by Platelet-Rich Plasma
title_short SAS-PRP Study: A Real-Life Satisfaction Assessment in Patients with Cartilage Lesions of the Knee Treated by Platelet-Rich Plasma
title_sort sas prp study a real life satisfaction assessment in patients with cartilage lesions of the knee treated by platelet rich plasma
topic platelet-rich plasma
osteoarthritis
knee
cartilage
intra-articular injection
SATMED-Q©
url https://www.mdpi.com/2306-5354/10/11/1276
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