Nano pharmaceutical delivery in combating colorectal cancer
Colorectal cancer (CRC), ranking as the third most common cancer globally, is associated with a high death rate. The colon, also known as the large intestine, is the site where colorectal cancer initially develops. It is a lengthy tube that facilitates the passage of digested food to the rectum and...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
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Elsevier
2024-02-01
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| Series: | Medicine in Drug Discovery |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S2590098623000234 |
| _version_ | 1827349021186850816 |
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| author | Sanju Kumari Singh Raghu Solanki Sunita Patel |
| author_facet | Sanju Kumari Singh Raghu Solanki Sunita Patel |
| author_sort | Sanju Kumari Singh |
| collection | DOAJ |
| description | Colorectal cancer (CRC), ranking as the third most common cancer globally, is associated with a high death rate. The colon, also known as the large intestine, is the site where colorectal cancer initially develops. It is a lengthy tube that facilitates the passage of digested food to the rectum and ultimately out of the body. CRC has the potential to affect other organs or regions of the body if not diagnosed or treated earlier. Delivering precise medications in a site-specific and target-oriented manner can improve chronic disease therapy in various ways. In recent years, there have been a number of innovations in nanomedicine (including chemotherapeutic medicines, biological agents, immunotherapeutic agents, and other such applications) for the treatment of various diseases, including CRC. The current review provides an up-to-date overview of the latest advancements in the field of nanomedicines and nano-based drug delivery systems for the CRC treatment. An in-depth investigation has been conducted into the study of nanomaterials such as liposomes, metal, polymeric and peptides nanomaterials, exploring their potential applications in enhancing the efficacy of both new and existing drugs. This review also focuses on the opportunities and challenges posed by nanomedicines in delivering drugs derived from natural and synthetic sources. Additionally, information on advancements and future prospects in the field of nanomedicine is provided. |
| first_indexed | 2024-03-08T00:23:01Z |
| format | Article |
| id | doaj.art-8d805b2900634871810290a6ddffd066 |
| institution | Directory Open Access Journal |
| issn | 2590-0986 |
| language | English |
| last_indexed | 2024-03-08T00:23:01Z |
| publishDate | 2024-02-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Medicine in Drug Discovery |
| spelling | doaj.art-8d805b2900634871810290a6ddffd0662024-02-16T04:30:02ZengElsevierMedicine in Drug Discovery2590-09862024-02-0121100173Nano pharmaceutical delivery in combating colorectal cancerSanju Kumari Singh0Raghu Solanki1Sunita Patel2School of Life Sciences, Central University of Gujarat, Gandhinagar 382030, IndiaSchool of Life Sciences, Central University of Gujarat, Gandhinagar 382030, IndiaCorresponding author.; School of Life Sciences, Central University of Gujarat, Gandhinagar 382030, IndiaColorectal cancer (CRC), ranking as the third most common cancer globally, is associated with a high death rate. The colon, also known as the large intestine, is the site where colorectal cancer initially develops. It is a lengthy tube that facilitates the passage of digested food to the rectum and ultimately out of the body. CRC has the potential to affect other organs or regions of the body if not diagnosed or treated earlier. Delivering precise medications in a site-specific and target-oriented manner can improve chronic disease therapy in various ways. In recent years, there have been a number of innovations in nanomedicine (including chemotherapeutic medicines, biological agents, immunotherapeutic agents, and other such applications) for the treatment of various diseases, including CRC. The current review provides an up-to-date overview of the latest advancements in the field of nanomedicines and nano-based drug delivery systems for the CRC treatment. An in-depth investigation has been conducted into the study of nanomaterials such as liposomes, metal, polymeric and peptides nanomaterials, exploring their potential applications in enhancing the efficacy of both new and existing drugs. This review also focuses on the opportunities and challenges posed by nanomedicines in delivering drugs derived from natural and synthetic sources. Additionally, information on advancements and future prospects in the field of nanomedicine is provided.http://www.sciencedirect.com/science/article/pii/S2590098623000234Colorectal cancerDrug deliveryNanomedicinePhytochemicals |
| spellingShingle | Sanju Kumari Singh Raghu Solanki Sunita Patel Nano pharmaceutical delivery in combating colorectal cancer Medicine in Drug Discovery Colorectal cancer Drug delivery Nanomedicine Phytochemicals |
| title | Nano pharmaceutical delivery in combating colorectal cancer |
| title_full | Nano pharmaceutical delivery in combating colorectal cancer |
| title_fullStr | Nano pharmaceutical delivery in combating colorectal cancer |
| title_full_unstemmed | Nano pharmaceutical delivery in combating colorectal cancer |
| title_short | Nano pharmaceutical delivery in combating colorectal cancer |
| title_sort | nano pharmaceutical delivery in combating colorectal cancer |
| topic | Colorectal cancer Drug delivery Nanomedicine Phytochemicals |
| url | http://www.sciencedirect.com/science/article/pii/S2590098623000234 |
| work_keys_str_mv | AT sanjukumarisingh nanopharmaceuticaldeliveryincombatingcolorectalcancer AT raghusolanki nanopharmaceuticaldeliveryincombatingcolorectalcancer AT sunitapatel nanopharmaceuticaldeliveryincombatingcolorectalcancer |