Perioperative Complications in Patients with Preeclampsia Undergoing Caesarean Section Surgery
Caesarean section has risks of bleeding, infection and thromboembolism, and neuroendocrine-metabolic, and inflammatory-immune responses that may worsen outcomes in patients with preeclampsia. There is little research examining perioperative, as opposed to peripartum, outcomes in patients with preecl...
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| Format: | Article |
| Language: | English |
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MDPI AG
2023-11-01
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| Series: | Journal of Clinical Medicine |
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| Online Access: | https://www.mdpi.com/2077-0383/12/22/7050 |
| _version_ | 1811153716425785344 |
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| author | Busra Sara Unal Alicia T. Dennis |
| author_facet | Busra Sara Unal Alicia T. Dennis |
| author_sort | Busra Sara Unal |
| collection | DOAJ |
| description | Caesarean section has risks of bleeding, infection and thromboembolism, and neuroendocrine-metabolic, and inflammatory-immune responses that may worsen outcomes in patients with preeclampsia. There is little research examining perioperative, as opposed to peripartum, outcomes in patients with preeclampsia. We conducted a single-centrecentre retrospective cohort study of perioperative patients with preeclampsia over an eight-month period to determine the rate of perioperative complication. Seventy-two patients were included. The maternal complication rate was 59.7 per 100 operations (95% CI 48.2 to 70.3%). Severe complications included pulmonary oedema 2 (2.8%), haemorrhage > 1000 mL 5 (6.9%), and blood transfusion 2 (2.8%). Twenty (27.8%) patients had a hospital length of stay ≥7 days. The rate of anaemia (haemoglobin < 110 g/L) on hospital discharge was 42 per 100 operations (95% CI 31.0 to 53.2%). Patient representation rate to hospital after discharge was 23.6% per 100 operations (95% CI 15.3 to 34.6%). There were no maternal deaths. The neonatal complication rate was 38.9 per 100 operations (95% CI 28.9 to 51.1%) with one foetal death. Patients with preeclampsia undergoing caesarean section are a very high-risk surgical group who experience significant perioperative complications. Urgent action is needed to confirm these findings and improve outcomes in these patients. |
| first_indexed | 2024-03-09T16:43:09Z |
| format | Article |
| id | doaj.art-8d840975c77249e0bd0d3e0f8bc95d73 |
| institution | Directory Open Access Journal |
| issn | 2077-0383 |
| language | English |
| last_indexed | 2024-03-09T16:43:09Z |
| publishDate | 2023-11-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Journal of Clinical Medicine |
| spelling | doaj.art-8d840975c77249e0bd0d3e0f8bc95d732023-11-24T14:49:17ZengMDPI AGJournal of Clinical Medicine2077-03832023-11-011222705010.3390/jcm12227050Perioperative Complications in Patients with Preeclampsia Undergoing Caesarean Section SurgeryBusra Sara Unal0Alicia T. Dennis1Hospital Medical Officer, Western Health, St Albans, VIC 3021, AustraliaThe Joan Kirner Women’s and Children’s Hospital, St Albans Sunshine Hospital, Western Health, St. Albans, VIC 3021, AustraliaCaesarean section has risks of bleeding, infection and thromboembolism, and neuroendocrine-metabolic, and inflammatory-immune responses that may worsen outcomes in patients with preeclampsia. There is little research examining perioperative, as opposed to peripartum, outcomes in patients with preeclampsia. We conducted a single-centrecentre retrospective cohort study of perioperative patients with preeclampsia over an eight-month period to determine the rate of perioperative complication. Seventy-two patients were included. The maternal complication rate was 59.7 per 100 operations (95% CI 48.2 to 70.3%). Severe complications included pulmonary oedema 2 (2.8%), haemorrhage > 1000 mL 5 (6.9%), and blood transfusion 2 (2.8%). Twenty (27.8%) patients had a hospital length of stay ≥7 days. The rate of anaemia (haemoglobin < 110 g/L) on hospital discharge was 42 per 100 operations (95% CI 31.0 to 53.2%). Patient representation rate to hospital after discharge was 23.6% per 100 operations (95% CI 15.3 to 34.6%). There were no maternal deaths. The neonatal complication rate was 38.9 per 100 operations (95% CI 28.9 to 51.1%) with one foetal death. Patients with preeclampsia undergoing caesarean section are a very high-risk surgical group who experience significant perioperative complications. Urgent action is needed to confirm these findings and improve outcomes in these patients.https://www.mdpi.com/2077-0383/12/22/7050hypertensionheart failurehaemorrhageperioperative complicationsobstetricspreeclampsia |
| spellingShingle | Busra Sara Unal Alicia T. Dennis Perioperative Complications in Patients with Preeclampsia Undergoing Caesarean Section Surgery Journal of Clinical Medicine hypertension heart failure haemorrhage perioperative complications obstetrics preeclampsia |
| title | Perioperative Complications in Patients with Preeclampsia Undergoing Caesarean Section Surgery |
| title_full | Perioperative Complications in Patients with Preeclampsia Undergoing Caesarean Section Surgery |
| title_fullStr | Perioperative Complications in Patients with Preeclampsia Undergoing Caesarean Section Surgery |
| title_full_unstemmed | Perioperative Complications in Patients with Preeclampsia Undergoing Caesarean Section Surgery |
| title_short | Perioperative Complications in Patients with Preeclampsia Undergoing Caesarean Section Surgery |
| title_sort | perioperative complications in patients with preeclampsia undergoing caesarean section surgery |
| topic | hypertension heart failure haemorrhage perioperative complications obstetrics preeclampsia |
| url | https://www.mdpi.com/2077-0383/12/22/7050 |
| work_keys_str_mv | AT busrasaraunal perioperativecomplicationsinpatientswithpreeclampsiaundergoingcaesareansectionsurgery AT aliciatdennis perioperativecomplicationsinpatientswithpreeclampsiaundergoingcaesareansectionsurgery |