The intrinsically disordered region of GCE protein adopts a more fixed structure by interacting with the LBD of the nuclear receptor FTZ-F1

The intrinsically disordered region of GCE protein adopts a more fixed structure by interacting with the LBD of the nuclear receptor FTZ-F1

Abstract The Drosophila melanogaster Germ cell-expressed protein (GCE) is a paralog of the juvenile hormone (JH) receptor - Methoprene tolerant protein (MET). Both proteins mediate JH function, preventing precocious differentiation during D. melanogaster development. Despite that GCE and MET are oft...

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Bibliographic Details
Main Authors: Marta Kolonko, Dominika Bystranowska, Michał Taube, Maciej Kozak, Mark Bostock, Grzegorz Popowicz, Andrzej Ożyhar, Beata Greb-Markiewicz
Format: Article
Language:English
Published: BMC 2020-11-01
Series:Cell Communication and Signaling
Subjects:
Germ cell-expressed protein
Intrinsically disordered proteins
bHLH-PAS transcription factor
C-terminus
Protein-protein interactions
FTZ-F1
Online Access:http://link.springer.com/article/10.1186/s12964-020-00662-2

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