Carotenoids Extraction from Orange Peels Using a Thymol-Based Hydrophobic Eutectic Solvent

The food industry produces substantial amounts of waste, which can cause a lot of environmental issues. However, such waste is also a valuable source of bioactive substances that can potentially be used either by the food industry or other types of industries, in the production of medicines, nutrace...

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Main Authors: Konstantinos Terlidis, Vassilis Athanasiadis, Theodoros Chatzimitakos, Eleni Bozinou, Stavros I. Lalas
Format: Article
Language:English
Published: MDPI AG 2023-09-01
Series:AppliedChem
Subjects:
Online Access:https://www.mdpi.com/2673-9623/3/4/28
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author Konstantinos Terlidis
Vassilis Athanasiadis
Theodoros Chatzimitakos
Eleni Bozinou
Stavros I. Lalas
author_facet Konstantinos Terlidis
Vassilis Athanasiadis
Theodoros Chatzimitakos
Eleni Bozinou
Stavros I. Lalas
author_sort Konstantinos Terlidis
collection DOAJ
description The food industry produces substantial amounts of waste, which can cause a lot of environmental issues. However, such waste is also a valuable source of bioactive substances that can potentially be used either by the food industry or other types of industries, in the production of medicines, nutraceuticals, cosmetics, etc. The present study proposes a novel approach to extract such bioactive compounds from orange peel waste using hydrophobic eutectic solvents synthesized with thymol and fatty acids (hexanoic and octanoic acid). A response surface methodology was employed to optimize the extraction conditions and achieve maximum recovery of carotenoids. The optimal hydrophobic eutectic solvent consisted of thymol and hexanoic acid at a molar ratio of 2:1, and the optimum extraction was achieved using a solvent-to-solid ratio of 12:1 and a temperature of 20 °C for 78 min; this resulted in a recovery of 259.45 μg of total carotenoids per g of dry matter, which is a significantly higher recovery compared to common organic solvents. Based on the above, it is demonstrated that hydrophobic eutectic solvents is a promising solvent that can be used to extract bioactive compounds from orange peel waste.
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spelling doaj.art-8d977de0b8a24d66a0bb7ade37184cc72023-12-22T13:48:43ZengMDPI AGAppliedChem2673-96232023-09-013443745110.3390/appliedchem3040028Carotenoids Extraction from Orange Peels Using a Thymol-Based Hydrophobic Eutectic SolventKonstantinos Terlidis0Vassilis Athanasiadis1Theodoros Chatzimitakos2Eleni Bozinou3Stavros I. Lalas4Department of Chemical Engineering, University of Western Macedonia, 50100 Kozani, GreeceDepartment of Food Science and Nutrition, University of Thessaly, 43100 Karditsa, GreeceDepartment of Food Science and Nutrition, University of Thessaly, 43100 Karditsa, GreeceDepartment of Food Science and Nutrition, University of Thessaly, 43100 Karditsa, GreeceDepartment of Food Science and Nutrition, University of Thessaly, 43100 Karditsa, GreeceThe food industry produces substantial amounts of waste, which can cause a lot of environmental issues. However, such waste is also a valuable source of bioactive substances that can potentially be used either by the food industry or other types of industries, in the production of medicines, nutraceuticals, cosmetics, etc. The present study proposes a novel approach to extract such bioactive compounds from orange peel waste using hydrophobic eutectic solvents synthesized with thymol and fatty acids (hexanoic and octanoic acid). A response surface methodology was employed to optimize the extraction conditions and achieve maximum recovery of carotenoids. The optimal hydrophobic eutectic solvent consisted of thymol and hexanoic acid at a molar ratio of 2:1, and the optimum extraction was achieved using a solvent-to-solid ratio of 12:1 and a temperature of 20 °C for 78 min; this resulted in a recovery of 259.45 μg of total carotenoids per g of dry matter, which is a significantly higher recovery compared to common organic solvents. Based on the above, it is demonstrated that hydrophobic eutectic solvents is a promising solvent that can be used to extract bioactive compounds from orange peel waste.https://www.mdpi.com/2673-9623/3/4/28hydrophobic deep eutectic solventsorange peel wastecarotenoidsantioxidantscolorresponse surface methodology
spellingShingle Konstantinos Terlidis
Vassilis Athanasiadis
Theodoros Chatzimitakos
Eleni Bozinou
Stavros I. Lalas
Carotenoids Extraction from Orange Peels Using a Thymol-Based Hydrophobic Eutectic Solvent
AppliedChem
hydrophobic deep eutectic solvents
orange peel waste
carotenoids
antioxidants
color
response surface methodology
title Carotenoids Extraction from Orange Peels Using a Thymol-Based Hydrophobic Eutectic Solvent
title_full Carotenoids Extraction from Orange Peels Using a Thymol-Based Hydrophobic Eutectic Solvent
title_fullStr Carotenoids Extraction from Orange Peels Using a Thymol-Based Hydrophobic Eutectic Solvent
title_full_unstemmed Carotenoids Extraction from Orange Peels Using a Thymol-Based Hydrophobic Eutectic Solvent
title_short Carotenoids Extraction from Orange Peels Using a Thymol-Based Hydrophobic Eutectic Solvent
title_sort carotenoids extraction from orange peels using a thymol based hydrophobic eutectic solvent
topic hydrophobic deep eutectic solvents
orange peel waste
carotenoids
antioxidants
color
response surface methodology
url https://www.mdpi.com/2673-9623/3/4/28
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