The Antiviral Small-Interfering RNA Pathway Induces Zika Virus Resistance in Transgenic <i>Aedes aegypti</i>

The Antiviral Small-Interfering RNA Pathway Induces Zika Virus Resistance in Transgenic <i>Aedes aegypti</i>

The resurgence of arbovirus outbreaks across the globe, including the recent Zika virus (ZIKV) epidemic in 2015–2016, emphasizes the need for innovative vector control methods. In this study, we investigated ZIKV susceptibility to transgenic <i>Aedes aegypti</i> engineered to target the...

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Bibliographic Details
Main Authors: Adeline E. Williams, Irma Sanchez-Vargas, William R. Reid, Jingyi Lin, Alexander W.E. Franz, Ken E. Olson
Format: Article
Language:English
Published: MDPI AG 2020-10-01
Series:Viruses
Subjects:
<i>Aedes aegypti</i>
Zika virus
transgenesis
RNAi
siRNAs
antiviral immunity
Online Access:https://www.mdpi.com/1999-4915/12/11/1231

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