Changes of non-specific resistance in patients with postoperative peritonitis with abdominal sepsis

<p><strong>Purpose:</strong> to study changes in nonspecific resistance and cytokine regulation in patients with postoperative peritonitis with abdominal sepsis</p><p><strong>Materials and methods.</strong> The clinic treated 456 patients with postoperative...

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Main Author: M. M. Droniak
Format: Article
Language:English
Published: Kazimierz Wielki University 2021-03-01
Series:Journal of Education, Health and Sport
Subjects:
Online Access:https://apcz.umk.pl/czasopisma/index.php/JEHS/article/view/34312
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author M. M. Droniak
author_facet M. M. Droniak
author_sort M. M. Droniak
collection DOAJ
description <p><strong>Purpose:</strong> to study changes in nonspecific resistance and cytokine regulation in patients with postoperative peritonitis with abdominal sepsis</p><p><strong>Materials and methods.</strong> The clinic treated 456 patients with postoperative peritonitis who were treated in the surgery department of the municipal non-profit enterprise Regional Clinical Hospital of Ivano-Frankivsk Regional Council in the period from 2000 to 2021. Immunological studies were performed in 66 patients with varying severity of abdominal sepsis and its complications.</p><p><strong>Research results and their discussion.</strong> In patients with postoperative peritonitis with abdominal sepsis, the phagocytic index during the first week of hospital stay was in control. However, on the 10th-11th day, the phagocytic index decreased 1.6 times, which progressed until the end of the third week of treatment - on the 14th-21st day, the phagocytic index was 2.7 times smaller than the control. The phagocytic count in patients with PP with abdominal sepsis reached maximum values in the first day of the disease (3 ± 0.26). Later in the treatment process, this figure gradually decreased and on day 14-21 came to normal and amounted to 1.96 ± 0.10. The index of completeness of phagocytosis on the first day of the disease was1,59 ± 0,20. By 2-3 days it decreased by 1.44 ± 0.20 and returned to normal by 14-21 days. Circulating immune complexes were normalized by 5-7 days of the disease.</p>
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spelling doaj.art-8d9b9f0afd73450a9da05ec28ed39faf2022-12-21T21:27:38ZengKazimierz Wielki UniversityJournal of Education, Health and Sport2391-83062021-03-0111323123810.12775/JEHS.2021.11.03.02227384Changes of non-specific resistance in patients with postoperative peritonitis with abdominal sepsisM. M. Droniak0Ivano-Frankivsk National Medical University<p><strong>Purpose:</strong> to study changes in nonspecific resistance and cytokine regulation in patients with postoperative peritonitis with abdominal sepsis</p><p><strong>Materials and methods.</strong> The clinic treated 456 patients with postoperative peritonitis who were treated in the surgery department of the municipal non-profit enterprise Regional Clinical Hospital of Ivano-Frankivsk Regional Council in the period from 2000 to 2021. Immunological studies were performed in 66 patients with varying severity of abdominal sepsis and its complications.</p><p><strong>Research results and their discussion.</strong> In patients with postoperative peritonitis with abdominal sepsis, the phagocytic index during the first week of hospital stay was in control. However, on the 10th-11th day, the phagocytic index decreased 1.6 times, which progressed until the end of the third week of treatment - on the 14th-21st day, the phagocytic index was 2.7 times smaller than the control. The phagocytic count in patients with PP with abdominal sepsis reached maximum values in the first day of the disease (3 ± 0.26). Later in the treatment process, this figure gradually decreased and on day 14-21 came to normal and amounted to 1.96 ± 0.10. The index of completeness of phagocytosis on the first day of the disease was1,59 ± 0,20. By 2-3 days it decreased by 1.44 ± 0.20 and returned to normal by 14-21 days. Circulating immune complexes were normalized by 5-7 days of the disease.</p>https://apcz.umk.pl/czasopisma/index.php/JEHS/article/view/34312postoperative peritonitisabdominal sepsis
spellingShingle M. M. Droniak
Changes of non-specific resistance in patients with postoperative peritonitis with abdominal sepsis
Journal of Education, Health and Sport
postoperative peritonitis
abdominal sepsis
title Changes of non-specific resistance in patients with postoperative peritonitis with abdominal sepsis
title_full Changes of non-specific resistance in patients with postoperative peritonitis with abdominal sepsis
title_fullStr Changes of non-specific resistance in patients with postoperative peritonitis with abdominal sepsis
title_full_unstemmed Changes of non-specific resistance in patients with postoperative peritonitis with abdominal sepsis
title_short Changes of non-specific resistance in patients with postoperative peritonitis with abdominal sepsis
title_sort changes of non specific resistance in patients with postoperative peritonitis with abdominal sepsis
topic postoperative peritonitis
abdominal sepsis
url https://apcz.umk.pl/czasopisma/index.php/JEHS/article/view/34312
work_keys_str_mv AT mmdroniak changesofnonspecificresistanceinpatientswithpostoperativeperitonitiswithabdominalsepsis