Good Bacteria and Worms: As Promising Candidates for Inflammatory Bowel Disease
The gastrointestinal system harbors various microorganisms, known as gut microbiota. Increase in prevalence of inflammatory bowel disease (IBD) in developed countries is associated with changes in the environment, such as decrease in incidence of parasitic infections, especially helminths, and chang...
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Format: | Article |
Language: | English |
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Mazandaran University of Medical Sciences
2018-09-01
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Series: | Journal of Mazandaran University of Medical Sciences |
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Online Access: | http://jmums.mazums.ac.ir/article-1-11394-en.html |
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author | Hossein Ghalehnoei Javad Akhtari Hamed Kalani Mahdi Fakhar |
author_facet | Hossein Ghalehnoei Javad Akhtari Hamed Kalani Mahdi Fakhar |
author_sort | Hossein Ghalehnoei |
collection | DOAJ |
description | The gastrointestinal system harbors various microorganisms, known as gut microbiota. Increase in prevalence of inflammatory bowel disease (IBD) in developed countries is associated with changes in the environment, such as decrease in incidence of parasitic infections, especially helminths, and changes in the intestinal flora. Probiotics are useful microbiota for human health. The parasitic worms (helminths) have evolved over the years with their host. Several studies have investigated the capability of helminths and probiotics to alter or control host immune responses in view of the fact that these organisms have immunomodulation effects. Given the contradictory results, further broad studies are needed to confirm the role of probiotics and helminths in the treatment of IBD. |
first_indexed | 2024-04-10T20:29:43Z |
format | Article |
id | doaj.art-8da06a69a64b4175b7ac16fc3db69898 |
institution | Directory Open Access Journal |
issn | 1735-9260 1735-9279 |
language | English |
last_indexed | 2024-04-10T20:29:43Z |
publishDate | 2018-09-01 |
publisher | Mazandaran University of Medical Sciences |
record_format | Article |
series | Journal of Mazandaran University of Medical Sciences |
spelling | doaj.art-8da06a69a64b4175b7ac16fc3db698982023-01-25T07:29:47ZengMazandaran University of Medical SciencesJournal of Mazandaran University of Medical Sciences1735-92601735-92792018-09-0128164179191Good Bacteria and Worms: As Promising Candidates for Inflammatory Bowel DiseaseHossein Ghalehnoei0Javad Akhtari1Hamed Kalani2Mahdi Fakhar3 Assistant Professor, Department of Medical Biotechnology, Molecular and Cell Biology Research Center, Faculty of Advanced Technologies in Medicine, Mazandaran University of Medical Sciences, Sari, Iran Assistant Professor, Department of Medical Nanotechnology, Immunogenetics Research Center, Faculty of Advanced Technologies in Medicine, Mazandaran University of Medical Sciences, Sari, Iran Assistant Professor, Infectious Diseases Research Center, Golestan University of Medical Sciences, Gorgan, Iran Associate Professor, Molecular and Cell Biology Research Center, Faculty of Medcine, Mazandaran University of Medical Sciences, Sari, Iran The gastrointestinal system harbors various microorganisms, known as gut microbiota. Increase in prevalence of inflammatory bowel disease (IBD) in developed countries is associated with changes in the environment, such as decrease in incidence of parasitic infections, especially helminths, and changes in the intestinal flora. Probiotics are useful microbiota for human health. The parasitic worms (helminths) have evolved over the years with their host. Several studies have investigated the capability of helminths and probiotics to alter or control host immune responses in view of the fact that these organisms have immunomodulation effects. Given the contradictory results, further broad studies are needed to confirm the role of probiotics and helminths in the treatment of IBD.http://jmums.mazums.ac.ir/article-1-11394-en.htmlprobioticshelminthsulcerative colitiscrohn’s disease |
spellingShingle | Hossein Ghalehnoei Javad Akhtari Hamed Kalani Mahdi Fakhar Good Bacteria and Worms: As Promising Candidates for Inflammatory Bowel Disease Journal of Mazandaran University of Medical Sciences probiotics helminths ulcerative colitis crohn’s disease |
title | Good Bacteria and Worms: As Promising Candidates for Inflammatory Bowel Disease |
title_full | Good Bacteria and Worms: As Promising Candidates for Inflammatory Bowel Disease |
title_fullStr | Good Bacteria and Worms: As Promising Candidates for Inflammatory Bowel Disease |
title_full_unstemmed | Good Bacteria and Worms: As Promising Candidates for Inflammatory Bowel Disease |
title_short | Good Bacteria and Worms: As Promising Candidates for Inflammatory Bowel Disease |
title_sort | good bacteria and worms as promising candidates for inflammatory bowel disease |
topic | probiotics helminths ulcerative colitis crohn’s disease |
url | http://jmums.mazums.ac.ir/article-1-11394-en.html |
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