A retrospective study regarding the influence of COVID-19 disease on asthma
Abstract Background During the Covid-19 pandemic patients suffering from asthma raised many concerns regarding the outcome ofthe impact of COVID-19 disease on their preexisting condition. The 2021 GINA report indicates that people with asthma do not appear to be at increased risk of a severe form of...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
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BMC
2023-01-01
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| Series: | BMC Pulmonary Medicine |
| Subjects: | |
| Online Access: | https://doi.org/10.1186/s12890-023-02309-7 |
| _version_ | 1797946097922998272 |
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| author | Ioana Adriana Muntean Polliana Mihaela Leru Irena Pintea Ioana Corina Bocsan Carmen Teodora Dobrican Diana Deleanu |
| author_facet | Ioana Adriana Muntean Polliana Mihaela Leru Irena Pintea Ioana Corina Bocsan Carmen Teodora Dobrican Diana Deleanu |
| author_sort | Ioana Adriana Muntean |
| collection | DOAJ |
| description | Abstract Background During the Covid-19 pandemic patients suffering from asthma raised many concerns regarding the outcome ofthe impact of COVID-19 disease on their preexisting condition. The 2021 GINA report indicates that people with asthma do not appear to be at increased risk of a severe form of COVID-19. Method This study is a retrospective study of patients (n = 163) median age = 27.8 years, M:F = 1:1.26, with asthma evaluated using ACT (asthma control test) and VAS (visual analog scale) before and after COVID-19 disease. An ACT score over 20 points placed patients in the controlled asthma group. Results The overall evaluation for COVID-19 in our asthma patients revealed that 22.7% of the studied group had the COVID-19 disease (21.5% in the controlled asthma group and 24.5% in uncontrolled asthma group). Asthma disease history was longer in the uncontroled asthma group (128 ± 96.8 months vs. 296 ± 59.7 months, p = 0.05). Asthma treatment was conducted according to the GINA guideline, and 18.4% (30 pts) of the patients were on allergen immunotherapy treatment. Significantly more uncontrolled patients were significantly more in Step 1 and 5 of treatment (p = 0.05 and p = 0.03). During the COVID-19 pandemic, patients in the GINA step 5 of treatment experienced a worsening of asthma, often twice as severe as compared to patients with asthma in GINA step 1–4. In these patients, even mild COVID-19 disease led to worsened asthma symptoms, while severe COVID-19 led to a severe asthma impairment measured by ACT score (p = 0.03) and VAS scale (p = 0.02), with increased oral corticosteroids consumption. Conclusion Maintaining optimal asthma control should be able to reduce risk of severe outcomes after COVID-19 disease. Communication via phone with the specialist involved in their asthma care was very comforting for patients, thus confirming the necessity to include phone calls, smart phone’s application or online evaluations and counseling in long-term care of chronic diseases. |
| first_indexed | 2024-04-10T21:05:30Z |
| format | Article |
| id | doaj.art-8dab22647b9f4db8b8a7dddef21ddc03 |
| institution | Directory Open Access Journal |
| issn | 1471-2466 |
| language | English |
| last_indexed | 2024-04-10T21:05:30Z |
| publishDate | 2023-01-01 |
| publisher | BMC |
| record_format | Article |
| series | BMC Pulmonary Medicine |
| spelling | doaj.art-8dab22647b9f4db8b8a7dddef21ddc032023-01-22T12:03:47ZengBMCBMC Pulmonary Medicine1471-24662023-01-012311910.1186/s12890-023-02309-7A retrospective study regarding the influence of COVID-19 disease on asthmaIoana Adriana Muntean0Polliana Mihaela Leru1Irena Pintea2Ioana Corina Bocsan3Carmen Teodora Dobrican4Diana Deleanu5Allergology Department, Department of Allergology and Immunology and “Octavian Fodor” Institute of Gastroenterology and Hepatology, “Iuliu Hatieganu” University of Medicine and PharmacyClinical Department 5, “Carol Davila” University of Medicine and PharmacyAllergology Department, Department of Allergology and Immunology and “Octavian Fodor” Institute of Gastroenterology and Hepatology, “Iuliu Hatieganu” University of Medicine and PharmacyDepartment of Pharmacology, Toxicology and Clinical Pharmacology, “Iuliu Hatieganu” University of Medicine and PharmacyAllergology Department, Department of Allergology and Immunology and “Octavian Fodor” Institute of Gastroenterology and Hepatology, “Iuliu Hatieganu” University of Medicine and PharmacyAllergology Department, Department of Allergology and Immunology and “Octavian Fodor” Institute of Gastroenterology and Hepatology, “Iuliu Hatieganu” University of Medicine and PharmacyAbstract Background During the Covid-19 pandemic patients suffering from asthma raised many concerns regarding the outcome ofthe impact of COVID-19 disease on their preexisting condition. The 2021 GINA report indicates that people with asthma do not appear to be at increased risk of a severe form of COVID-19. Method This study is a retrospective study of patients (n = 163) median age = 27.8 years, M:F = 1:1.26, with asthma evaluated using ACT (asthma control test) and VAS (visual analog scale) before and after COVID-19 disease. An ACT score over 20 points placed patients in the controlled asthma group. Results The overall evaluation for COVID-19 in our asthma patients revealed that 22.7% of the studied group had the COVID-19 disease (21.5% in the controlled asthma group and 24.5% in uncontrolled asthma group). Asthma disease history was longer in the uncontroled asthma group (128 ± 96.8 months vs. 296 ± 59.7 months, p = 0.05). Asthma treatment was conducted according to the GINA guideline, and 18.4% (30 pts) of the patients were on allergen immunotherapy treatment. Significantly more uncontrolled patients were significantly more in Step 1 and 5 of treatment (p = 0.05 and p = 0.03). During the COVID-19 pandemic, patients in the GINA step 5 of treatment experienced a worsening of asthma, often twice as severe as compared to patients with asthma in GINA step 1–4. In these patients, even mild COVID-19 disease led to worsened asthma symptoms, while severe COVID-19 led to a severe asthma impairment measured by ACT score (p = 0.03) and VAS scale (p = 0.02), with increased oral corticosteroids consumption. Conclusion Maintaining optimal asthma control should be able to reduce risk of severe outcomes after COVID-19 disease. Communication via phone with the specialist involved in their asthma care was very comforting for patients, thus confirming the necessity to include phone calls, smart phone’s application or online evaluations and counseling in long-term care of chronic diseases.https://doi.org/10.1186/s12890-023-02309-7AsthmaCOVID-19 pandemicChronic diseasesLong-term careSARS-CoV-2 infection |
| spellingShingle | Ioana Adriana Muntean Polliana Mihaela Leru Irena Pintea Ioana Corina Bocsan Carmen Teodora Dobrican Diana Deleanu A retrospective study regarding the influence of COVID-19 disease on asthma BMC Pulmonary Medicine Asthma COVID-19 pandemic Chronic diseases Long-term care SARS-CoV-2 infection |
| title | A retrospective study regarding the influence of COVID-19 disease on asthma |
| title_full | A retrospective study regarding the influence of COVID-19 disease on asthma |
| title_fullStr | A retrospective study regarding the influence of COVID-19 disease on asthma |
| title_full_unstemmed | A retrospective study regarding the influence of COVID-19 disease on asthma |
| title_short | A retrospective study regarding the influence of COVID-19 disease on asthma |
| title_sort | retrospective study regarding the influence of covid 19 disease on asthma |
| topic | Asthma COVID-19 pandemic Chronic diseases Long-term care SARS-CoV-2 infection |
| url | https://doi.org/10.1186/s12890-023-02309-7 |
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