Kdm2b Regulates Somatic Reprogramming through Variant PRC1 Complex-Dependent Function

Kdm2b Regulates Somatic Reprogramming through Variant PRC1 Complex-Dependent Function

Polycomb repressive complex 1 (PRC1) plays essential roles in cell-fate determination. Recent studies have found that the composition of mammalian PRC1 is particularly varied and complex; however, little is known about the functional consequences of these variant PRC1 complexes on cell-fate determin...

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Bibliographic Details
Main Authors: Zhiwei Zhou, Xuejie Yang, Jiangping He, Jing Liu, Fang Wu, Shengyong Yu, Yuting Liu, Runxia Lin, He Liu, Yuanbin Cui, Chunhua Zhou, Xiaoshan Wang, Jian Wu, Shangtao Cao, Lin Guo, Lihui Lin, Tao Wang, Xiaozhong Peng, Boqing Qiang, Andrew P. Hutchins, Duanqing Pei, Jiekai Chen
Format: Article
Language:English
Published: Elsevier 2017-11-01
Series:Cell Reports
Subjects:
reprogramming
Polycomb repressive complex 1
PRC1
Kdm2b
BMP signaling
epigenetic regulation
variant PRC1
iPS
pluripotency
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124717315711

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