ESOMEPRAZOL IN TREATMENT OF GASTROESOPHAGIAL REFLUX DISEASE IN CHILDREN AND ADOLESCENTS

The results of trials of activity of esomeprazol in children with gastroesophagial reflux disease (gerd) are presented in this article. It was marked that esomeprazol (Nexium) can be used in children of 1–11 years (10 or 20 mg daily) and 12–17 years (20 or 40 mg daily) with gerd according to modern...

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Main Author: R.T. Saygitov
Format: Article
Language:English
Published: "Paediatrician" Publishers LLC 2008-08-01
Series:Вопросы современной педиатрии
Online Access:https://vsp.spr-journal.ru/jour/article/view/1441
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author R.T. Saygitov
author_facet R.T. Saygitov
author_sort R.T. Saygitov
collection DOAJ
description The results of trials of activity of esomeprazol in children with gastroesophagial reflux disease (gerd) are presented in this article. It was marked that esomeprazol (Nexium) can be used in children of 1–11 years (10 or 20 mg daily) and 12–17 years (20 or 40 mg daily) with gerd according to modern recommendations. The information about acid suppressor activity of esomeprazol in children with gerd younger then 2 years old (0,25–1 mg/kg daily) was published. Clinical activity of esomeprazol was confirmed in a number of randomized and open labeled, developed in different countries, including Russia. At the same time main results of activity of this medication were obtained in investigations of adult patients with gerd. This fact indicates necessity of provision of wide ranging trials, which could make complete assessment of advantages and safety profile of esomeprazol.Key words: children, adolescents, gastroesophagial reflux disease, esomeprazol, treatment.
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spelling doaj.art-8db08cb15d6e4c3d80c4e1bf447b58412023-09-03T10:32:35Zeng"Paediatrician" Publishers LLCВопросы современной педиатрии1682-55271682-55352008-08-01741321351441ESOMEPRAZOL IN TREATMENT OF GASTROESOPHAGIAL REFLUX DISEASE IN CHILDREN AND ADOLESCENTSR.T. Saygitov0Научный центр здоровья детей РАМН, МоскваThe results of trials of activity of esomeprazol in children with gastroesophagial reflux disease (gerd) are presented in this article. It was marked that esomeprazol (Nexium) can be used in children of 1–11 years (10 or 20 mg daily) and 12–17 years (20 or 40 mg daily) with gerd according to modern recommendations. The information about acid suppressor activity of esomeprazol in children with gerd younger then 2 years old (0,25–1 mg/kg daily) was published. Clinical activity of esomeprazol was confirmed in a number of randomized and open labeled, developed in different countries, including Russia. At the same time main results of activity of this medication were obtained in investigations of adult patients with gerd. This fact indicates necessity of provision of wide ranging trials, which could make complete assessment of advantages and safety profile of esomeprazol.Key words: children, adolescents, gastroesophagial reflux disease, esomeprazol, treatment.https://vsp.spr-journal.ru/jour/article/view/1441
spellingShingle R.T. Saygitov
ESOMEPRAZOL IN TREATMENT OF GASTROESOPHAGIAL REFLUX DISEASE IN CHILDREN AND ADOLESCENTS
Вопросы современной педиатрии
title ESOMEPRAZOL IN TREATMENT OF GASTROESOPHAGIAL REFLUX DISEASE IN CHILDREN AND ADOLESCENTS
title_full ESOMEPRAZOL IN TREATMENT OF GASTROESOPHAGIAL REFLUX DISEASE IN CHILDREN AND ADOLESCENTS
title_fullStr ESOMEPRAZOL IN TREATMENT OF GASTROESOPHAGIAL REFLUX DISEASE IN CHILDREN AND ADOLESCENTS
title_full_unstemmed ESOMEPRAZOL IN TREATMENT OF GASTROESOPHAGIAL REFLUX DISEASE IN CHILDREN AND ADOLESCENTS
title_short ESOMEPRAZOL IN TREATMENT OF GASTROESOPHAGIAL REFLUX DISEASE IN CHILDREN AND ADOLESCENTS
title_sort esomeprazol in treatment of gastroesophagial reflux disease in children and adolescents
url https://vsp.spr-journal.ru/jour/article/view/1441
work_keys_str_mv AT rtsaygitov esomeprazolintreatmentofgastroesophagialrefluxdiseaseinchildrenandadolescents