The PD-L1 metabolic interactome intersects with choline metabolism and inflammation

The PD-L1 metabolic interactome intersects with choline metabolism and inflammation

Abstract Background Harnessing the power of the immune system by using immune checkpoint inhibitors has resulted in some of the most exciting advances in cancer treatment. The full potential of this approach has, however, not been fully realized for treating many cancers such as pancreatic and breas...

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Bibliographic Details
Main Authors: Jesus Pacheco-Torres, Marie-France Penet, Yelena Mironchik, Balaji Krishnamachary, Zaver M. Bhujwalla
Format: Article
Language:English
Published: BMC 2021-02-01
Series:Cancer & Metabolism
Subjects:
Immune checkpoints
PD-L1
Choline kinase alpha
COX-2
Breast cancer
Online Access:https://doi.org/10.1186/s40170-021-00245-w

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