Cyanobactins from Cyanobacteria: Current Genetic and Chemical State of Knowledge
Cyanobacteria are considered to be one of the most promising sources of new, natural products. Apart from non-ribosomal peptides and polyketides, ribosomally synthesized and post-translationally modified peptides (RiPPs) are one of the leading groups of bioactive compounds produced by cyanobacteria....
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Format: | Article |
Language: | English |
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MDPI AG
2015-11-01
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Series: | Marine Drugs |
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Online Access: | http://www.mdpi.com/1660-3397/13/11/6910 |
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author | Joana Martins Vitor Vasconcelos |
author_facet | Joana Martins Vitor Vasconcelos |
author_sort | Joana Martins |
collection | DOAJ |
description | Cyanobacteria are considered to be one of the most promising sources of new, natural products. Apart from non-ribosomal peptides and polyketides, ribosomally synthesized and post-translationally modified peptides (RiPPs) are one of the leading groups of bioactive compounds produced by cyanobacteria. Among these, cyanobactins have sparked attention due to their interesting bioactivities and for their potential to be prospective candidates in the development of drugs. It is assumed that the primary source of cyanobactins is cyanobacteria, although these compounds have also been isolated from marine animals such as ascidians, sponges and mollusks. The aim of this review is to update the current knowledge of cyanobactins, recognized as being produced by cyanobacteria, and to emphasize their genetic clusters and chemical structures as well as their bioactivities, ecological roles and biotechnological potential. |
first_indexed | 2024-04-12T19:47:38Z |
format | Article |
id | doaj.art-8db6eff7ed7843b0a4276857ddb83704 |
institution | Directory Open Access Journal |
issn | 1660-3397 |
language | English |
last_indexed | 2024-04-12T19:47:38Z |
publishDate | 2015-11-01 |
publisher | MDPI AG |
record_format | Article |
series | Marine Drugs |
spelling | doaj.art-8db6eff7ed7843b0a4276857ddb837042022-12-22T03:18:54ZengMDPI AGMarine Drugs1660-33972015-11-0113116910694610.3390/md13116910md13116910Cyanobactins from Cyanobacteria: Current Genetic and Chemical State of KnowledgeJoana Martins0Vitor Vasconcelos1Faculty of Sciences, University of Porto, Rua do Campo Alegre, Porto 4169-007, PortugalFaculty of Sciences, University of Porto, Rua do Campo Alegre, Porto 4169-007, PortugalCyanobacteria are considered to be one of the most promising sources of new, natural products. Apart from non-ribosomal peptides and polyketides, ribosomally synthesized and post-translationally modified peptides (RiPPs) are one of the leading groups of bioactive compounds produced by cyanobacteria. Among these, cyanobactins have sparked attention due to their interesting bioactivities and for their potential to be prospective candidates in the development of drugs. It is assumed that the primary source of cyanobactins is cyanobacteria, although these compounds have also been isolated from marine animals such as ascidians, sponges and mollusks. The aim of this review is to update the current knowledge of cyanobactins, recognized as being produced by cyanobacteria, and to emphasize their genetic clusters and chemical structures as well as their bioactivities, ecological roles and biotechnological potential.http://www.mdpi.com/1660-3397/13/11/6910cyanobacteriacyanobactinsgenetic clusterschemical structuresbioactivitiesecological rolesbiotechnological potential |
spellingShingle | Joana Martins Vitor Vasconcelos Cyanobactins from Cyanobacteria: Current Genetic and Chemical State of Knowledge Marine Drugs cyanobacteria cyanobactins genetic clusters chemical structures bioactivities ecological roles biotechnological potential |
title | Cyanobactins from Cyanobacteria: Current Genetic and Chemical State of Knowledge |
title_full | Cyanobactins from Cyanobacteria: Current Genetic and Chemical State of Knowledge |
title_fullStr | Cyanobactins from Cyanobacteria: Current Genetic and Chemical State of Knowledge |
title_full_unstemmed | Cyanobactins from Cyanobacteria: Current Genetic and Chemical State of Knowledge |
title_short | Cyanobactins from Cyanobacteria: Current Genetic and Chemical State of Knowledge |
title_sort | cyanobactins from cyanobacteria current genetic and chemical state of knowledge |
topic | cyanobacteria cyanobactins genetic clusters chemical structures bioactivities ecological roles biotechnological potential |
url | http://www.mdpi.com/1660-3397/13/11/6910 |
work_keys_str_mv | AT joanamartins cyanobactinsfromcyanobacteriacurrentgeneticandchemicalstateofknowledge AT vitorvasconcelos cyanobactinsfromcyanobacteriacurrentgeneticandchemicalstateofknowledge |