Cyanobactins from Cyanobacteria: Current Genetic and Chemical State of Knowledge

Cyanobacteria are considered to be one of the most promising sources of new, natural products. Apart from non-ribosomal peptides and polyketides, ribosomally synthesized and post-translationally modified peptides (RiPPs) are one of the leading groups of bioactive compounds produced by cyanobacteria....

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Main Authors: Joana Martins, Vitor Vasconcelos
Format: Article
Language:English
Published: MDPI AG 2015-11-01
Series:Marine Drugs
Subjects:
Online Access:http://www.mdpi.com/1660-3397/13/11/6910
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author Joana Martins
Vitor Vasconcelos
author_facet Joana Martins
Vitor Vasconcelos
author_sort Joana Martins
collection DOAJ
description Cyanobacteria are considered to be one of the most promising sources of new, natural products. Apart from non-ribosomal peptides and polyketides, ribosomally synthesized and post-translationally modified peptides (RiPPs) are one of the leading groups of bioactive compounds produced by cyanobacteria. Among these, cyanobactins have sparked attention due to their interesting bioactivities and for their potential to be prospective candidates in the development of drugs. It is assumed that the primary source of cyanobactins is cyanobacteria, although these compounds have also been isolated from marine animals such as ascidians, sponges and mollusks. The aim of this review is to update the current knowledge of cyanobactins, recognized as being produced by cyanobacteria, and to emphasize their genetic clusters and chemical structures as well as their bioactivities, ecological roles and biotechnological potential.
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spelling doaj.art-8db6eff7ed7843b0a4276857ddb837042022-12-22T03:18:54ZengMDPI AGMarine Drugs1660-33972015-11-0113116910694610.3390/md13116910md13116910Cyanobactins from Cyanobacteria: Current Genetic and Chemical State of KnowledgeJoana Martins0Vitor Vasconcelos1Faculty of Sciences, University of Porto, Rua do Campo Alegre, Porto 4169-007, PortugalFaculty of Sciences, University of Porto, Rua do Campo Alegre, Porto 4169-007, PortugalCyanobacteria are considered to be one of the most promising sources of new, natural products. Apart from non-ribosomal peptides and polyketides, ribosomally synthesized and post-translationally modified peptides (RiPPs) are one of the leading groups of bioactive compounds produced by cyanobacteria. Among these, cyanobactins have sparked attention due to their interesting bioactivities and for their potential to be prospective candidates in the development of drugs. It is assumed that the primary source of cyanobactins is cyanobacteria, although these compounds have also been isolated from marine animals such as ascidians, sponges and mollusks. The aim of this review is to update the current knowledge of cyanobactins, recognized as being produced by cyanobacteria, and to emphasize their genetic clusters and chemical structures as well as their bioactivities, ecological roles and biotechnological potential.http://www.mdpi.com/1660-3397/13/11/6910cyanobacteriacyanobactinsgenetic clusterschemical structuresbioactivitiesecological rolesbiotechnological potential
spellingShingle Joana Martins
Vitor Vasconcelos
Cyanobactins from Cyanobacteria: Current Genetic and Chemical State of Knowledge
Marine Drugs
cyanobacteria
cyanobactins
genetic clusters
chemical structures
bioactivities
ecological roles
biotechnological potential
title Cyanobactins from Cyanobacteria: Current Genetic and Chemical State of Knowledge
title_full Cyanobactins from Cyanobacteria: Current Genetic and Chemical State of Knowledge
title_fullStr Cyanobactins from Cyanobacteria: Current Genetic and Chemical State of Knowledge
title_full_unstemmed Cyanobactins from Cyanobacteria: Current Genetic and Chemical State of Knowledge
title_short Cyanobactins from Cyanobacteria: Current Genetic and Chemical State of Knowledge
title_sort cyanobactins from cyanobacteria current genetic and chemical state of knowledge
topic cyanobacteria
cyanobactins
genetic clusters
chemical structures
bioactivities
ecological roles
biotechnological potential
url http://www.mdpi.com/1660-3397/13/11/6910
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AT vitorvasconcelos cyanobactinsfromcyanobacteriacurrentgeneticandchemicalstateofknowledge