Serum cytokine change profile associated with HBsAg loss during combination therapy with PEG-IFN-α in NAs-suppressed chronic hepatitis B patients

Serum cytokine change profile associated with HBsAg loss during combination therapy with PEG-IFN-α in NAs-suppressed chronic hepatitis B patients

ObjectiveThe aim of this study was to explore the profile of cytokine changes during the combination therapy with pegylated interferon alpha (PEG-IFN-α) and its relationship with HBsAg loss in nucleos(t)ide analogs (NAs)-suppressed chronic hepatitis B patients.MethodsSeventy-six patients with chroni...

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Bibliographic Details
Main Authors: Wen-Xin Wang, Rui Jia, Xue-Yuan Jin, Xiaoyan Li, Shuang-Nan Zhou, Xiao-Ning Zhang, Chun-Bao Zhou, Fu-Sheng Wang, Junliang Fu
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-01-01
Series:Frontiers in Immunology
Subjects:
chronic hepatitis B
cytokine
CXCL-10
HBsAg loss
combined treatment
Peg-IFN-α
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2023.1121778/full

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