Synthesis of New 2,3-Dihydroindole Derivatives and Evaluation of Their Melatonin Receptor Binding Affinity

Synthesis of New 2,3-Dihydroindole Derivatives and Evaluation of Their Melatonin Receptor Binding Affinity

2,3-Dihydroindoles are promising agents for the synthesis of new compounds with neuroprotective and antioxidant properties. Usually, these compounds are obtained by direct reduction of the corresponding indoles containing acceptor groups in the indole ring for its activation. In this work, we propos...

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Bibliographic Details
Main Authors: Maria S. Volkova, Alexander M. Efremov, Elena N. Bezsonova, Michael D. Tsymliakov, Anita I. Maksutova, Maria A. Salykina, Sergey E. Sosonyuk, Elena F. Shevtsova, Natalia A. Lozinskaya
Format: Article
Language:English
Published: MDPI AG 2022-11-01
Series:Molecules
Subjects:
2,3-dihydroindole
2-chloromelatonin
chemoselective reduction
melatonin
nitrile reduction
2-oxindole reduction
Online Access:https://www.mdpi.com/1420-3049/27/21/7462

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