Radiation Therapy for the Treatment of Recurrent Glioblastoma: An Overview
Despite the therapeutic advances in neuro-oncology, most patients with glioblastoma ultimately experience local progression/relapse. Re-irradiation has been poorly viewed in the past, mainly due to the overestimated risk of side effects using conventional radiotherapy. To date, thanks to the improve...
| Main Authors: | , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
MDPI AG
2012-03-01
|
| Series: | Cancers |
| Subjects: | |
| Online Access: | http://www.mdpi.com/2072-6694/4/1/257/ |
| _version_ | 1797757974903521280 |
|---|---|
| author | Maurizio Amichetti Dante Amelio |
| author_facet | Maurizio Amichetti Dante Amelio |
| author_sort | Maurizio Amichetti |
| collection | DOAJ |
| description | Despite the therapeutic advances in neuro-oncology, most patients with glioblastoma ultimately experience local progression/relapse. Re-irradiation has been poorly viewed in the past, mainly due to the overestimated risk of side effects using conventional radiotherapy. To date, thanks to the improvement of several delivery techniques, together with improved imaging capabilities, re-irradiation is a viable salvage treatment option to manage such clinical scenario. A literature overview on the feasibility and efficacy of the different irradiation modalities for recurrent glioblastoma along with considerations on areas of improvement are provided. |
| first_indexed | 2024-03-12T18:23:15Z |
| format | Article |
| id | doaj.art-8dbed671233c4fbeb5324ccbf5559c3d |
| institution | Directory Open Access Journal |
| issn | 2072-6694 |
| language | English |
| last_indexed | 2024-03-12T18:23:15Z |
| publishDate | 2012-03-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Cancers |
| spelling | doaj.art-8dbed671233c4fbeb5324ccbf5559c3d2023-08-02T08:42:58ZengMDPI AGCancers2072-66942012-03-014125728010.3390/cancers4010257Radiation Therapy for the Treatment of Recurrent Glioblastoma: An OverviewMaurizio AmichettiDante AmelioDespite the therapeutic advances in neuro-oncology, most patients with glioblastoma ultimately experience local progression/relapse. Re-irradiation has been poorly viewed in the past, mainly due to the overestimated risk of side effects using conventional radiotherapy. To date, thanks to the improvement of several delivery techniques, together with improved imaging capabilities, re-irradiation is a viable salvage treatment option to manage such clinical scenario. A literature overview on the feasibility and efficacy of the different irradiation modalities for recurrent glioblastoma along with considerations on areas of improvement are provided.http://www.mdpi.com/2072-6694/4/1/257/glioblastomarecurrenceradiation therapy |
| spellingShingle | Maurizio Amichetti Dante Amelio Radiation Therapy for the Treatment of Recurrent Glioblastoma: An Overview Cancers glioblastoma recurrence radiation therapy |
| title | Radiation Therapy for the Treatment of Recurrent Glioblastoma: An Overview |
| title_full | Radiation Therapy for the Treatment of Recurrent Glioblastoma: An Overview |
| title_fullStr | Radiation Therapy for the Treatment of Recurrent Glioblastoma: An Overview |
| title_full_unstemmed | Radiation Therapy for the Treatment of Recurrent Glioblastoma: An Overview |
| title_short | Radiation Therapy for the Treatment of Recurrent Glioblastoma: An Overview |
| title_sort | radiation therapy for the treatment of recurrent glioblastoma an overview |
| topic | glioblastoma recurrence radiation therapy |
| url | http://www.mdpi.com/2072-6694/4/1/257/ |
| work_keys_str_mv | AT maurizioamichetti radiationtherapyforthetreatmentofrecurrentglioblastomaanoverview AT danteamelio radiationtherapyforthetreatmentofrecurrentglioblastomaanoverview |