Preclinical testing of dabigatran in trypsin-dependent pancreatitis
Pancreatitis, the inflammatory disorder of the pancreas, has no specific therapy. Genetic, biochemical, and animal model studies revealed that trypsin plays a central role in the onset and progression of pancreatitis. Here, we performed biochemical and preclinical mouse experiments to offer proof of...
Main Authors: | Zsófia Gabriella Pesei, Zsanett Jancsó, Alexandra Demcsák, Balázs Csaba Németh, Sandor Vajda, Miklós Sahin-Tóth |
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Format: | Article |
Language: | English |
Published: |
American Society for Clinical investigation
2022-11-01
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Series: | JCI Insight |
Subjects: | |
Online Access: | https://doi.org/10.1172/jci.insight.161145 |
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