Systems biology analysis of gene expression during in vivo Mycobacterium avium paratuberculosis enteric colonization reveals role for immune tolerance.

Systems biology analysis of gene expression during in vivo Mycobacterium avium paratuberculosis enteric colonization reveals role for immune tolerance.

Survival and persistence of Mycobacterium avium subsp. paratuberculosis (MAP) in the intestinal mucosa is associated with host immune tolerance. However, the initial events during MAP interaction with its host that lead to pathogen survival, granulomatous inflammation, and clinical disease progressi...

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Main Authors: Sangeeta Khare, Sara D Lawhon, Kenneth L Drake, Jairo E S Nunes, Josely F Figueiredo, Carlos A Rossetti, Tamara Gull, Robin E Everts, Harris A Lewin, Cristi L Galindo, Harold R Garner, Leslie Garry Adams
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3422314?pdf=render

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