CEACAM1 long isoform has opposite effects on the growth of human mastocytosis and medullary thyroid carcinoma cells

CEACAM1 long isoform has opposite effects on the growth of human mastocytosis and medullary thyroid carcinoma cells

Abstract Carcinoembryonic antigen‐related cell adhesion molecule 1 (CEACAM1) is expressed in a number of tumor cell types. The immunoreceptor tyrosine‐based inhibitory motif (ITIM)‐containing isoforms of this molecule which possess a long cytoplasmic tail (CEACAM1‐L) generally play inhibitory roles...

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Bibliographic Details
Main Authors: Chiyuki Ueshima, Tatsuki R. Kataoka, Yusuke Takei, Masahiro Hirata, Akihiko Sugimoto, Mitsuyoshi Hirokawa, Yoshimichi Okayama, Richard S. Blumberg, Hironori Haga
Format: Article
Language:English
Published: Wiley 2017-04-01
Series:Cancer Medicine
Subjects:
CEACAM1
mast cell
medullary thyroid carcinoma
SHP‐1
Src family kinases
Online Access:https://doi.org/10.1002/cam4.1050

Internet

https://doi.org/10.1002/cam4.1050

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