Colloid cyst of third ventricle: Histopathological and ultrastructural study
Cysts occupying the third ventricle are rare lesions and may appear as an unusual cause of hydrocephalic crisis. A 40-year old woman with headache and one episode of fainting attack was diagnosed with a cystic lesion in the third ventricle after brain MRI study. She was operated with the pre-operati...
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| Format: | Article |
| Language: | English |
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Association of Clinical Pathologists of Nepal
2019-09-01
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| Series: | Journal of Pathology of Nepal |
| Subjects: | |
| Online Access: | https://www.nepjol.info/index.php/JPN/article/view/24882 |
| _version_ | 1818276861218652160 |
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| author | Prasanna Karki Sameer Chhetri Aryal Gopi Aryal Rajesh Panth Manoj Bohara Sumit Joshi Prakash Paudel Damber Bikram Shah Gopal Raman Sharma |
| author_facet | Prasanna Karki Sameer Chhetri Aryal Gopi Aryal Rajesh Panth Manoj Bohara Sumit Joshi Prakash Paudel Damber Bikram Shah Gopal Raman Sharma |
| author_sort | Prasanna Karki |
| collection | DOAJ |
| description | Cysts occupying the third ventricle are rare lesions and may appear as an unusual cause of hydrocephalic crisis. A 40-year old woman with headache and one episode of fainting attack was diagnosed with a cystic lesion in the third ventricle after brain MRI study. She was operated with the pre-operative diagnosis of a colloid cyst. A yellowish, thick and mucoid cyst was observed intra-operatively. The total removal of the cyst was done along with the cyst wall. On histopathological evaluation, the cyst wall was lined by ciliated cuboidal to pseudostratified columnar epithelium resting on an eosinophilic basement membrane. The ultrastructural study showed the characteristic 9+2 pattern of cilia. Immunohistochemistry showed positive staining for epithelial membrane antigen (EMA), cytokeratin (CK), and negative staining for Glial fibrillary acidic protein (GFAP). Histopathological and ultrastructural findings confirm the diagnosis of a colloid cyst of third ventricles favoring the endodermal origin of the cyst. |
| first_indexed | 2024-12-12T22:52:22Z |
| format | Article |
| id | doaj.art-8dc44d296774489c97f768e86bcd6ab5 |
| institution | Directory Open Access Journal |
| issn | 2091-0797 2091-0908 |
| language | English |
| last_indexed | 2024-12-12T22:52:22Z |
| publishDate | 2019-09-01 |
| publisher | Association of Clinical Pathologists of Nepal |
| record_format | Article |
| series | Journal of Pathology of Nepal |
| spelling | doaj.art-8dc44d296774489c97f768e86bcd6ab52022-12-22T00:09:02ZengAssociation of Clinical Pathologists of NepalJournal of Pathology of Nepal2091-07972091-09082019-09-01921590159410.3126/jpn.v9i2.2488224882Colloid cyst of third ventricle: Histopathological and ultrastructural studyPrasanna Karki0Sameer Chhetri Aryal1Gopi Aryal2Rajesh Panth3Manoj Bohara4Sumit Joshi5Prakash Paudel6Damber Bikram Shah7Gopal Raman Sharma8Neurosurgery Division, Nepal Mediciti Hospital, Kathmandu, NepalNepal Mediciti Hospital, Lalitpur, NepalNepal Mediciti Hospital, Lalitpur, NepalNepal Mediciti Hospital, Lalitpur, NepalNepal Mediciti Hospital, Kathmandu, NepalNepal Mediciti Hospital, Lalitpur, NepalNepal Mediciti Hospital, Lalitpur, NepalNepal Mediciti Hospital, Lalitpur, NepalNepal Mediciti Hospital, Lalitpur, NepalCysts occupying the third ventricle are rare lesions and may appear as an unusual cause of hydrocephalic crisis. A 40-year old woman with headache and one episode of fainting attack was diagnosed with a cystic lesion in the third ventricle after brain MRI study. She was operated with the pre-operative diagnosis of a colloid cyst. A yellowish, thick and mucoid cyst was observed intra-operatively. The total removal of the cyst was done along with the cyst wall. On histopathological evaluation, the cyst wall was lined by ciliated cuboidal to pseudostratified columnar epithelium resting on an eosinophilic basement membrane. The ultrastructural study showed the characteristic 9+2 pattern of cilia. Immunohistochemistry showed positive staining for epithelial membrane antigen (EMA), cytokeratin (CK), and negative staining for Glial fibrillary acidic protein (GFAP). Histopathological and ultrastructural findings confirm the diagnosis of a colloid cyst of third ventricles favoring the endodermal origin of the cyst.https://www.nepjol.info/index.php/JPN/article/view/24882colloid cysthydocephalusthird ventricle |
| spellingShingle | Prasanna Karki Sameer Chhetri Aryal Gopi Aryal Rajesh Panth Manoj Bohara Sumit Joshi Prakash Paudel Damber Bikram Shah Gopal Raman Sharma Colloid cyst of third ventricle: Histopathological and ultrastructural study Journal of Pathology of Nepal colloid cyst hydocephalus third ventricle |
| title | Colloid cyst of third ventricle: Histopathological and ultrastructural study |
| title_full | Colloid cyst of third ventricle: Histopathological and ultrastructural study |
| title_fullStr | Colloid cyst of third ventricle: Histopathological and ultrastructural study |
| title_full_unstemmed | Colloid cyst of third ventricle: Histopathological and ultrastructural study |
| title_short | Colloid cyst of third ventricle: Histopathological and ultrastructural study |
| title_sort | colloid cyst of third ventricle histopathological and ultrastructural study |
| topic | colloid cyst hydocephalus third ventricle |
| url | https://www.nepjol.info/index.php/JPN/article/view/24882 |
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