Nonsurgical Treatment of Male Infertility: Non-Specific Therapy
In male infertility, all possible known causes should be carefully evaluated and if detected, targeted treatment options for the cause should be implemented. The known causes of male infertility such as hypogonadotropic hypogonadism, hyperprolactinemia, genital tract infections, disorders of ejacula...
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| Format: | Article |
| Language: | English |
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Duzce University
2022-10-01
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| Series: | Düzce Tıp Fakültesi Dergisi |
| Subjects: | |
| Online Access: | https://dergipark.org.tr/en/download/article-file/2680488 |
| _version_ | 1827612535443947520 |
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| author | Metin Öztürk Emre Tokuç |
| author_facet | Metin Öztürk Emre Tokuç |
| author_sort | Metin Öztürk |
| collection | DOAJ |
| description | In male infertility, all possible known causes should be carefully evaluated and if detected, targeted treatment options for the cause should be implemented. The known causes of male infertility such as hypogonadotropic hypogonadism, hyperprolactinemia, genital tract infections, disorders of ejaculation, thyroid hormone disorders and varicocele can be treated efficiently by targeted therapies or surgical corrections. Unfortunately, these known causes cover about 20% of male infertility and the rest remains idiopathic. On the other hand, management of idiopathic, unexplained male infertility, in which no etiological factors can be found, is a challenge for both the clinician and couples seeking solutions. In the era of assisted reproductive technology, few medical options in this regard are still available with limited benefits and low scientific foundation based on theoretical concepts but empirical medical therapy continues as a mostly off-label option for obtaining a natural pregnancy. Comprehending the hypothalamic-pituitary-gonadal axis and the regulation of hormones is crucial in this regard. Empirical therapies have the potential to overcome overtreatment with assisted reproductive technology yet clinicians and couples must be aware of the limitations of empirical therapies and should be counseled in this direction. In this review, non-specific medical treatment options for idiopathic male infertility were covered. |
| first_indexed | 2024-03-09T08:25:42Z |
| format | Article |
| id | doaj.art-8dc4573148324ad98a744c2fe7dfedfa |
| institution | Directory Open Access Journal |
| issn | 1307-671X |
| language | English |
| last_indexed | 2024-03-09T08:25:42Z |
| publishDate | 2022-10-01 |
| publisher | Duzce University |
| record_format | Article |
| series | Düzce Tıp Fakültesi Dergisi |
| spelling | doaj.art-8dc4573148324ad98a744c2fe7dfedfa2023-12-02T21:11:32ZengDuzce UniversityDüzce Tıp Fakültesi Dergisi1307-671X2022-10-0124Special Issue262910.18678/dtfd.118234097Nonsurgical Treatment of Male Infertility: Non-Specific TherapyMetin Öztürk0Emre Tokuç1SAĞLIK BİLİMLERİ ÜNİVERSİTESİ, İSTANBUL HAYDARPAŞA NUMUNE SAĞLIK UYGULAMA VE ARAŞTIRMA MERKEZİSAĞLIK BİLİMLERİ ÜNİVERSİTESİ, İSTANBUL HAYDARPAŞA NUMUNE SAĞLIK UYGULAMA VE ARAŞTIRMA MERKEZİIn male infertility, all possible known causes should be carefully evaluated and if detected, targeted treatment options for the cause should be implemented. The known causes of male infertility such as hypogonadotropic hypogonadism, hyperprolactinemia, genital tract infections, disorders of ejaculation, thyroid hormone disorders and varicocele can be treated efficiently by targeted therapies or surgical corrections. Unfortunately, these known causes cover about 20% of male infertility and the rest remains idiopathic. On the other hand, management of idiopathic, unexplained male infertility, in which no etiological factors can be found, is a challenge for both the clinician and couples seeking solutions. In the era of assisted reproductive technology, few medical options in this regard are still available with limited benefits and low scientific foundation based on theoretical concepts but empirical medical therapy continues as a mostly off-label option for obtaining a natural pregnancy. Comprehending the hypothalamic-pituitary-gonadal axis and the regulation of hormones is crucial in this regard. Empirical therapies have the potential to overcome overtreatment with assisted reproductive technology yet clinicians and couples must be aware of the limitations of empirical therapies and should be counseled in this direction. In this review, non-specific medical treatment options for idiopathic male infertility were covered.https://dergipark.org.tr/en/download/article-file/2680488erkek infertilitesimedikal tedaviampirik tedavimale infertilitymedical treatmentempiric therapy |
| spellingShingle | Metin Öztürk Emre Tokuç Nonsurgical Treatment of Male Infertility: Non-Specific Therapy Düzce Tıp Fakültesi Dergisi erkek infertilitesi medikal tedavi ampirik tedavi male infertility medical treatment empiric therapy |
| title | Nonsurgical Treatment of Male Infertility: Non-Specific Therapy |
| title_full | Nonsurgical Treatment of Male Infertility: Non-Specific Therapy |
| title_fullStr | Nonsurgical Treatment of Male Infertility: Non-Specific Therapy |
| title_full_unstemmed | Nonsurgical Treatment of Male Infertility: Non-Specific Therapy |
| title_short | Nonsurgical Treatment of Male Infertility: Non-Specific Therapy |
| title_sort | nonsurgical treatment of male infertility non specific therapy |
| topic | erkek infertilitesi medikal tedavi ampirik tedavi male infertility medical treatment empiric therapy |
| url | https://dergipark.org.tr/en/download/article-file/2680488 |
| work_keys_str_mv | AT metinozturk nonsurgicaltreatmentofmaleinfertilitynonspecifictherapy AT emretokuc nonsurgicaltreatmentofmaleinfertilitynonspecifictherapy |