Free Brick1 is a trimeric precursor in the assembly of a functional wave complex.

Free Brick1 is a trimeric precursor in the assembly of a functional wave complex.

<h4>Background</h4>The Wave complex activates the Arp2/3 complex, inducing actin polymerization in lamellipodia and membrane ruffles. The Wave complex is composed of five subunits, the smallest of which, Brick1/Hspc300 (Brk1), is the least characterized. We previously reported that, unli...

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Bibliographic Details
Main Authors: Emmanuel Derivery, Jenny Fink, Davy Martin, Anne Houdusse, Matthieu Piel, Theresia E Stradal, Daniel Louvard, Alexis Gautreau
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2008-06-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/18560548/pdf/?tool=EBI

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