The effects of okadaic acid on Enchytraeus crypticus (Annelida: Oligochaeta)
We describe the morpho-functional effects of different concentrations of okadaic acid (OA) on specimens of Enchytraeus crypticus. The results demonstrate that this experimental model is very sensitive to the treatment and presents time- and dose-related effects mainly involving an immune response as...
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
| Published: |
University of Modena and Reggio Emilia
2006-11-01
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| Series: | Invertebrate Survival Journal |
| Subjects: | |
| Online Access: | http://www.isj.unimo.it/articoli/ISJ126.pdf |
| _version_ | 1819226542288404480 |
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| author | A Franchini M Marchetti |
| author_facet | A Franchini M Marchetti |
| author_sort | A Franchini |
| collection | DOAJ |
| description | We describe the morpho-functional effects of different concentrations of okadaic acid (OA) on specimens of Enchytraeus crypticus. The results demonstrate that this experimental model is very sensitive to the treatment and presents time- and dose-related effects mainly involving an immune response associated with a reaction in the chloragogenous tissue. At the lower dose (100 nM), the main organs do not appear particularly affected except for a swelling of the coelomatic cavity and an increased number of circulating coelomocytes. At the higher dose (200 nM), the chloragogenous tissue extends in volume to occupy the body cavity almost completely, while the circulating amoebocytes and chloragocytic cells undergo conformational changes. At the highest OA dose (400 nM), there is a general cell suffering in the main animal organs. In control animals, the immunocytochemical reaction with anti-IL-6 antibody is positive in neuron cell bodies and fibres from the ventral nerve cord and in circulating amoebocytes. Following OA treatment, fewer immunoreactive cells are seen in the damaged nervous tissue, and the high number of recruited amoebocytes is also positive. |
| first_indexed | 2024-12-23T10:27:09Z |
| format | Article |
| id | doaj.art-8dc5ddf01d7c446582b2022890a575ec |
| institution | Directory Open Access Journal |
| issn | 1824-307X |
| language | English |
| last_indexed | 2024-12-23T10:27:09Z |
| publishDate | 2006-11-01 |
| publisher | University of Modena and Reggio Emilia |
| record_format | Article |
| series | Invertebrate Survival Journal |
| spelling | doaj.art-8dc5ddf01d7c446582b2022890a575ec2022-12-21T17:50:31ZengUniversity of Modena and Reggio EmiliaInvertebrate Survival Journal1824-307X2006-11-0132111117The effects of okadaic acid on Enchytraeus crypticus (Annelida: Oligochaeta)A FranchiniM MarchettiWe describe the morpho-functional effects of different concentrations of okadaic acid (OA) on specimens of Enchytraeus crypticus. The results demonstrate that this experimental model is very sensitive to the treatment and presents time- and dose-related effects mainly involving an immune response associated with a reaction in the chloragogenous tissue. At the lower dose (100 nM), the main organs do not appear particularly affected except for a swelling of the coelomatic cavity and an increased number of circulating coelomocytes. At the higher dose (200 nM), the chloragogenous tissue extends in volume to occupy the body cavity almost completely, while the circulating amoebocytes and chloragocytic cells undergo conformational changes. At the highest OA dose (400 nM), there is a general cell suffering in the main animal organs. In control animals, the immunocytochemical reaction with anti-IL-6 antibody is positive in neuron cell bodies and fibres from the ventral nerve cord and in circulating amoebocytes. Following OA treatment, fewer immunoreactive cells are seen in the damaged nervous tissue, and the high number of recruited amoebocytes is also positive.http://www.isj.unimo.it/articoli/ISJ126.pdfAnnelidEnchytraeus crypticusokadaic acidIL-6-like molecules |
| spellingShingle | A Franchini M Marchetti The effects of okadaic acid on Enchytraeus crypticus (Annelida: Oligochaeta) Invertebrate Survival Journal Annelid Enchytraeus crypticus okadaic acid IL-6-like molecules |
| title | The effects of okadaic acid on Enchytraeus crypticus (Annelida: Oligochaeta) |
| title_full | The effects of okadaic acid on Enchytraeus crypticus (Annelida: Oligochaeta) |
| title_fullStr | The effects of okadaic acid on Enchytraeus crypticus (Annelida: Oligochaeta) |
| title_full_unstemmed | The effects of okadaic acid on Enchytraeus crypticus (Annelida: Oligochaeta) |
| title_short | The effects of okadaic acid on Enchytraeus crypticus (Annelida: Oligochaeta) |
| title_sort | effects of okadaic acid on enchytraeus crypticus annelida oligochaeta |
| topic | Annelid Enchytraeus crypticus okadaic acid IL-6-like molecules |
| url | http://www.isj.unimo.it/articoli/ISJ126.pdf |
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