miR-708-5p and miR-34c-5p are involved in nNOS regulation in dystrophic context

miR-708-5p and miR-34c-5p are involved in nNOS regulation in dystrophic context

Abstract Background Duchenne (DMD) and Becker (BMD) muscular dystrophies are caused by mutations in the DMD gene coding for dystrophin, a protein being part of a large sarcolemmal protein scaffold that includes the neuronal nitric oxide synthase (nNOS). The nNOS was shown to play critical roles in a...

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Main Authors: Marine Guilbaud, Christel Gentil, Cécile Peccate, Elena Gargaun, Isabelle Holtzmann, Carole Gruszczynski, Sestina Falcone, Kamel Mamchaoui, Rabah Ben Yaou, France Leturcq, Laurence Jeanson-Leh, France Piétri-Rouxel
Format: Article
Language:English
Published: BMC 2018-04-01
Series:Skeletal Muscle
Subjects:
Duchenne muscular dystrophy (DMD)
Becker muscular dystrophy (BMD)
miRNA
nNOS
Online Access:http://link.springer.com/article/10.1186/s13395-018-0161-2

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