Use of non-conventional biomarkers in the early diagnosis of acute kidney injury in preterm newborns with sepsis
Abstract Acute kidney injury (AKI) is a common finding in Neotatal Intensive Care Units (NICU). Sepsis is one the main causes of AKI in preterm newborns. AKI has been associated with significant death rates. Early detection of the condition is the first step to improving prevention, treatment, and o...
| Main Authors: | , , , , , , |
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| Format: | Article |
| Language: | English |
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Sociedade Brasileira de Nefrologia
2021-11-01
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| Series: | Brazilian Journal of Nephrology |
| Subjects: | |
| Online Access: | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0101-28002021005080301&tlng=en |
| _version_ | 1798026444593430528 |
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| author | Joycilene da Silva Barbosa Geraldo Bezerra da Silva Júnior Gdayllon Cavalcante Meneses Alice Maria Costa Martins Elizabeth De Francesco Daher Rosângela Pinheiro Gonçalves Machado Romélia Pinheiro Gonçalves Lemes |
| author_facet | Joycilene da Silva Barbosa Geraldo Bezerra da Silva Júnior Gdayllon Cavalcante Meneses Alice Maria Costa Martins Elizabeth De Francesco Daher Rosângela Pinheiro Gonçalves Machado Romélia Pinheiro Gonçalves Lemes |
| author_sort | Joycilene da Silva Barbosa |
| collection | DOAJ |
| description | Abstract Acute kidney injury (AKI) is a common finding in Neotatal Intensive Care Units (NICU). Sepsis is one the main causes of AKI in preterm newborns. AKI has been associated with significant death rates. Early detection of the condition is the first step to improving prevention, treatment, and outcomes, while decreasing length of hospitalization, care costs, and morbimortality. AKI may progress to chronic kidney disease (CKD), a condition linked with dialysis and greater risk of cardiovascular disease. This review article aims to discuss cases of AKI in preterm newborns with sepsis, the use of biomarkers in lab workup, and the use of non-conventional biomarkers for the early identification of AKI. |
| first_indexed | 2024-04-11T18:35:40Z |
| format | Article |
| id | doaj.art-8dc827aca89343bfbe07027976312240 |
| institution | Directory Open Access Journal |
| issn | 2175-8239 |
| language | English |
| last_indexed | 2024-04-11T18:35:40Z |
| publishDate | 2021-11-01 |
| publisher | Sociedade Brasileira de Nefrologia |
| record_format | Article |
| series | Brazilian Journal of Nephrology |
| spelling | doaj.art-8dc827aca89343bfbe070279763122402022-12-22T04:09:18ZengSociedade Brasileira de NefrologiaBrazilian Journal of Nephrology2175-82392021-11-0110.1590/2175-8239-jbn-2020-0222Use of non-conventional biomarkers in the early diagnosis of acute kidney injury in preterm newborns with sepsisJoycilene da Silva Barbosahttps://orcid.org/0000-0001-6637-402XGeraldo Bezerra da Silva Júniorhttps://orcid.org/0000-0002-8971-0994Gdayllon Cavalcante Meneseshttps://orcid.org/0000-0002-0160-5728Alice Maria Costa Martinshttps://orcid.org/0000-0001-8160-2027Elizabeth De Francesco Daherhttps://orcid.org/0000-0003-4189-1738Rosângela Pinheiro Gonçalves Machadohttps://orcid.org/0000-0002-1260-2346Romélia Pinheiro Gonçalves Lemeshttps://orcid.org/0000-0003-3178-412XAbstract Acute kidney injury (AKI) is a common finding in Neotatal Intensive Care Units (NICU). Sepsis is one the main causes of AKI in preterm newborns. AKI has been associated with significant death rates. Early detection of the condition is the first step to improving prevention, treatment, and outcomes, while decreasing length of hospitalization, care costs, and morbimortality. AKI may progress to chronic kidney disease (CKD), a condition linked with dialysis and greater risk of cardiovascular disease. This review article aims to discuss cases of AKI in preterm newborns with sepsis, the use of biomarkers in lab workup, and the use of non-conventional biomarkers for the early identification of AKI.http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0101-28002021005080301&tlng=enAcute Kidney InjurySepsisInfant, PrematureBiomarkers |
| spellingShingle | Joycilene da Silva Barbosa Geraldo Bezerra da Silva Júnior Gdayllon Cavalcante Meneses Alice Maria Costa Martins Elizabeth De Francesco Daher Rosângela Pinheiro Gonçalves Machado Romélia Pinheiro Gonçalves Lemes Use of non-conventional biomarkers in the early diagnosis of acute kidney injury in preterm newborns with sepsis Brazilian Journal of Nephrology Acute Kidney Injury Sepsis Infant, Premature Biomarkers |
| title | Use of non-conventional biomarkers in the early diagnosis of acute kidney injury in preterm newborns with sepsis |
| title_full | Use of non-conventional biomarkers in the early diagnosis of acute kidney injury in preterm newborns with sepsis |
| title_fullStr | Use of non-conventional biomarkers in the early diagnosis of acute kidney injury in preterm newborns with sepsis |
| title_full_unstemmed | Use of non-conventional biomarkers in the early diagnosis of acute kidney injury in preterm newborns with sepsis |
| title_short | Use of non-conventional biomarkers in the early diagnosis of acute kidney injury in preterm newborns with sepsis |
| title_sort | use of non conventional biomarkers in the early diagnosis of acute kidney injury in preterm newborns with sepsis |
| topic | Acute Kidney Injury Sepsis Infant, Premature Biomarkers |
| url | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0101-28002021005080301&tlng=en |
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