Characterization of acute kidney injury among Mexican patients with cirrhosis

Introduction and Objectives: Acute kidney injury is common in patients with cirrhosis and consists of various phenotypes; the first stage was divided into 2 phases; stage 1B has similar mortality to the higher stages; creatinine is not the best marker, limited by sarcopenia in cirrhosis. This study...

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Main Authors: MY Carmona-Castillo, F Higuera-de la Tijera, JL Pérez-Hernández, CS Tinitana -Jumbo, S Teutli-Carrion, EJ Medina–Avalos, CL Dorantes-Nava
Format: Article
Language:English
Published: Elsevier 2022-12-01
Series:Annals of Hepatology
Online Access:http://www.sciencedirect.com/science/article/pii/S1665268122001466
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author MY Carmona-Castillo
F Higuera-de la Tijera
JL Pérez-Hernández
CS Tinitana -Jumbo
S Teutli-Carrion
EJ Medina–Avalos
CL Dorantes-Nava
author_facet MY Carmona-Castillo
F Higuera-de la Tijera
JL Pérez-Hernández
CS Tinitana -Jumbo
S Teutli-Carrion
EJ Medina–Avalos
CL Dorantes-Nava
author_sort MY Carmona-Castillo
collection DOAJ
description Introduction and Objectives: Acute kidney injury is common in patients with cirrhosis and consists of various phenotypes; the first stage was divided into 2 phases; stage 1B has similar mortality to the higher stages; creatinine is not the best marker, limited by sarcopenia in cirrhosis. This study aimed to determine the characteristics of acute kidney injury in Mexican patients with cirrhosis and to evaluate its progression. Materials and Methods: Retrospective, descriptive study, including cirrhotic patients of any etiology who developed acute kidney injury. The characteristics and progression of the disease were evaluated according to treatment and possible markers, describing the quantitative variables as mean and standard deviation for the qualitative variables in frequencies and percentages. Results: Ninety patients were included, 62.2% men, mean age 52 ±11, 55.5% of alcoholic etiology followed by unknown and NASH (26 and 13% respectively), 4.4% in stage A, 3.5% in stage B and 58.8% in stage C for Child-Pugh; 31.1% with ACLF. The characteristics of renal failure are shown in Table 1 and the progression in Table 2. Conclusions: Renal failure in Mexican cirrhotic patients is low (30%), as is mortality (4%). Funding: The resources used in this study were from the hospital without any additional financing Declaration of interest: The authors declare no potential conflicts of interest.
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spelling doaj.art-8dce365de709408db1260469c77912652022-12-22T03:45:27ZengElsevierAnnals of Hepatology1665-26812022-12-0127100804Characterization of acute kidney injury among Mexican patients with cirrhosisMY Carmona-Castillo0F Higuera-de la Tijera1JL Pérez-Hernández2CS Tinitana -Jumbo3S Teutli-Carrion4EJ Medina–Avalos5CL Dorantes-Nava6Gastroenterology and Hepatology Service, General Hospital of Mexico “Dr. Eduardo Liceaga”, Mexico CityGastroenterology and Hepatology Service, General Hospital of Mexico “Dr. Eduardo Liceaga”, Mexico CityGastroenterology and Hepatology Service, General Hospital of Mexico “Dr. Eduardo Liceaga”, Mexico CityGastroenterology and Hepatology Service, General Hospital of Mexico “Dr. Eduardo Liceaga”, Mexico CityGastroenterology and Hepatology Service, General Hospital of Mexico “Dr. Eduardo Liceaga”, Mexico CityGastroenterology and Hepatology Service, General Hospital of Mexico “Dr. Eduardo Liceaga”, Mexico CityGastroenterology and Hepatology Service, General Hospital of Mexico “Dr. Eduardo Liceaga”, Mexico CityIntroduction and Objectives: Acute kidney injury is common in patients with cirrhosis and consists of various phenotypes; the first stage was divided into 2 phases; stage 1B has similar mortality to the higher stages; creatinine is not the best marker, limited by sarcopenia in cirrhosis. This study aimed to determine the characteristics of acute kidney injury in Mexican patients with cirrhosis and to evaluate its progression. Materials and Methods: Retrospective, descriptive study, including cirrhotic patients of any etiology who developed acute kidney injury. The characteristics and progression of the disease were evaluated according to treatment and possible markers, describing the quantitative variables as mean and standard deviation for the qualitative variables in frequencies and percentages. Results: Ninety patients were included, 62.2% men, mean age 52 ±11, 55.5% of alcoholic etiology followed by unknown and NASH (26 and 13% respectively), 4.4% in stage A, 3.5% in stage B and 58.8% in stage C for Child-Pugh; 31.1% with ACLF. The characteristics of renal failure are shown in Table 1 and the progression in Table 2. Conclusions: Renal failure in Mexican cirrhotic patients is low (30%), as is mortality (4%). Funding: The resources used in this study were from the hospital without any additional financing Declaration of interest: The authors declare no potential conflicts of interest.http://www.sciencedirect.com/science/article/pii/S1665268122001466
spellingShingle MY Carmona-Castillo
F Higuera-de la Tijera
JL Pérez-Hernández
CS Tinitana -Jumbo
S Teutli-Carrion
EJ Medina–Avalos
CL Dorantes-Nava
Characterization of acute kidney injury among Mexican patients with cirrhosis
Annals of Hepatology
title Characterization of acute kidney injury among Mexican patients with cirrhosis
title_full Characterization of acute kidney injury among Mexican patients with cirrhosis
title_fullStr Characterization of acute kidney injury among Mexican patients with cirrhosis
title_full_unstemmed Characterization of acute kidney injury among Mexican patients with cirrhosis
title_short Characterization of acute kidney injury among Mexican patients with cirrhosis
title_sort characterization of acute kidney injury among mexican patients with cirrhosis
url http://www.sciencedirect.com/science/article/pii/S1665268122001466
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AT jlperezhernandez characterizationofacutekidneyinjuryamongmexicanpatientswithcirrhosis
AT cstinitanajumbo characterizationofacutekidneyinjuryamongmexicanpatientswithcirrhosis
AT steutlicarrion characterizationofacutekidneyinjuryamongmexicanpatientswithcirrhosis
AT ejmedinaavalos characterizationofacutekidneyinjuryamongmexicanpatientswithcirrhosis
AT cldorantesnava characterizationofacutekidneyinjuryamongmexicanpatientswithcirrhosis