A cross-sectional anti-SARS coV-2 seroprevalence study among healthcare workers in a tertiary care hospital of eastern India
Purpose: Seroprevalence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in a cohort of health care workers (HCWs) in our tertiary health care set-up and determine the association of seroconversion with demographic characteristics, level of exposure, job responsibilities, and clinical...
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| Format: | Article |
| Language: | English |
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Wolters Kluwer Medknow Publications
2022-01-01
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| Series: | Journal of Dr. NTR University of Health Sciences |
| Subjects: | |
| Online Access: | http://www.jdrntruhs.org/article.asp?issn=2277-8632;year=2022;volume=11;issue=2;spage=113;epage=117;aulast=Chandra |
| _version_ | 1798037527672651776 |
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| author | Samatirtha Chandra Roumi Ghosh Md Khalid Rashid |
| author_facet | Samatirtha Chandra Roumi Ghosh Md Khalid Rashid |
| author_sort | Samatirtha Chandra |
| collection | DOAJ |
| description | Purpose: Seroprevalence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in a cohort of health care workers (HCWs) in our tertiary health care set-up and determine the association of seroconversion with demographic characteristics, level of exposure, job responsibilities, and clinical symptoms of HCWs exposed to COVID-19 patients.
Method: An observational cross-sectional epidemiological study was conducted in the Department of Microbiology, ESI-Postgraduate Institute of Medical Science and Research (PGIMSR), Kolkata. The study population was hospital staff who deliver care and services to patients
Result: A total of 242 HCWs participated in this cross-sectional study. Among the study population, 161 (66.5%) were male, and 81 (33.5%) were females, and the median age was 43 years. Of all, 22.7% were physicians, 22.3% nurses, 15.7% lab technician. A total of 16 HCWs had reported having diabetes mellitus, 7 chronic lung diseases, and 4 cardiac diseases. Out of 242 participants, 30 (12.4%) HCWs were found to be anti-SARS-CoV-2 IgG antibody positive after 4 months of duty in COVID hospital. Seropositivity rate was more among the age group 18–44 years (76.7%) and doctors (33.3%) than other disciplines. Around 31.4% (76/242) of them had high-risk exposure with either COVID patients or samples, and 18.4% became seropositive. A total of 59.1% HCWs gave the history of known or suspected contact with COVID patients in the household, and 14.7% turned seropositive. A total of 84.8% of those participants, who attended in-house training on infection control practices, remained seronegative.
Conclusion: In conclusion, the cross-sectional serology study in a tertiary care hospital in Kolkata revealed 30 (12.4%) HCWs had positive serology responses to SARS-CoV-2 out of 242 participants. Though there was an infection control policy and practice in the hospital to prevent the disease transmission, high-risk exposure and presence of comorbidities were definite risk factors for acquiring disease in our study. |
| first_indexed | 2024-04-11T21:27:45Z |
| format | Article |
| id | doaj.art-8dcfc8f9772f4d8c83d2d55047d4c9e5 |
| institution | Directory Open Access Journal |
| issn | 2277-8632 |
| language | English |
| last_indexed | 2024-04-11T21:27:45Z |
| publishDate | 2022-01-01 |
| publisher | Wolters Kluwer Medknow Publications |
| record_format | Article |
| series | Journal of Dr. NTR University of Health Sciences |
| spelling | doaj.art-8dcfc8f9772f4d8c83d2d55047d4c9e52022-12-22T04:02:19ZengWolters Kluwer Medknow PublicationsJournal of Dr. NTR University of Health Sciences2277-86322022-01-0111211311710.4103/jdrntruhs.jdrntruhs_90_21A cross-sectional anti-SARS coV-2 seroprevalence study among healthcare workers in a tertiary care hospital of eastern IndiaSamatirtha ChandraRoumi GhoshMd Khalid RashidPurpose: Seroprevalence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in a cohort of health care workers (HCWs) in our tertiary health care set-up and determine the association of seroconversion with demographic characteristics, level of exposure, job responsibilities, and clinical symptoms of HCWs exposed to COVID-19 patients. Method: An observational cross-sectional epidemiological study was conducted in the Department of Microbiology, ESI-Postgraduate Institute of Medical Science and Research (PGIMSR), Kolkata. The study population was hospital staff who deliver care and services to patients Result: A total of 242 HCWs participated in this cross-sectional study. Among the study population, 161 (66.5%) were male, and 81 (33.5%) were females, and the median age was 43 years. Of all, 22.7% were physicians, 22.3% nurses, 15.7% lab technician. A total of 16 HCWs had reported having diabetes mellitus, 7 chronic lung diseases, and 4 cardiac diseases. Out of 242 participants, 30 (12.4%) HCWs were found to be anti-SARS-CoV-2 IgG antibody positive after 4 months of duty in COVID hospital. Seropositivity rate was more among the age group 18–44 years (76.7%) and doctors (33.3%) than other disciplines. Around 31.4% (76/242) of them had high-risk exposure with either COVID patients or samples, and 18.4% became seropositive. A total of 59.1% HCWs gave the history of known or suspected contact with COVID patients in the household, and 14.7% turned seropositive. A total of 84.8% of those participants, who attended in-house training on infection control practices, remained seronegative. Conclusion: In conclusion, the cross-sectional serology study in a tertiary care hospital in Kolkata revealed 30 (12.4%) HCWs had positive serology responses to SARS-CoV-2 out of 242 participants. Though there was an infection control policy and practice in the hospital to prevent the disease transmission, high-risk exposure and presence of comorbidities were definite risk factors for acquiring disease in our study.http://www.jdrntruhs.org/article.asp?issn=2277-8632;year=2022;volume=11;issue=2;spage=113;epage=117;aulast=Chandraanti sars-cov-2 antibodycovid-19health care workerseroprevalence |
| spellingShingle | Samatirtha Chandra Roumi Ghosh Md Khalid Rashid A cross-sectional anti-SARS coV-2 seroprevalence study among healthcare workers in a tertiary care hospital of eastern India Journal of Dr. NTR University of Health Sciences anti sars-cov-2 antibody covid-19 health care worker seroprevalence |
| title | A cross-sectional anti-SARS coV-2 seroprevalence study among healthcare workers in a tertiary care hospital of eastern India |
| title_full | A cross-sectional anti-SARS coV-2 seroprevalence study among healthcare workers in a tertiary care hospital of eastern India |
| title_fullStr | A cross-sectional anti-SARS coV-2 seroprevalence study among healthcare workers in a tertiary care hospital of eastern India |
| title_full_unstemmed | A cross-sectional anti-SARS coV-2 seroprevalence study among healthcare workers in a tertiary care hospital of eastern India |
| title_short | A cross-sectional anti-SARS coV-2 seroprevalence study among healthcare workers in a tertiary care hospital of eastern India |
| title_sort | cross sectional anti sars cov 2 seroprevalence study among healthcare workers in a tertiary care hospital of eastern india |
| topic | anti sars-cov-2 antibody covid-19 health care worker seroprevalence |
| url | http://www.jdrntruhs.org/article.asp?issn=2277-8632;year=2022;volume=11;issue=2;spage=113;epage=117;aulast=Chandra |
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