Serum Antigenome Profiling Reveals Diagnostic Models for Rheumatoid Arthritis

Serum Antigenome Profiling Reveals Diagnostic Models for Rheumatoid Arthritis

ObjectiveThe study aimed to investigate the serum antigenomic profiling in rheumatoid arthritis (RA) and determine potential diagnostic biomarkers using label-free proteomic technology implemented with machine-learning algorithm.MethodSerum antigens were captured from a cohort consisting of 60 RA pa...

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Bibliographic Details
Main Authors: Peng Han, Chao Hou, Xi Zheng, Lulu Cao, Xiaomeng Shi, Xiaohui Zhang, Hua Ye, Hudan Pan, Liang Liu, Tingting Li, Fanlei Hu, Zhanguo Li
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-04-01
Series:Frontiers in Immunology
Subjects:
rheumatoid arthritis
antigenome
biomarkers
mass spectrometry
random forest
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2022.884462/full

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