Does endometrial receptivity array improve reproductive outcomes in euploid embryo transfer cycles? a systematic review
Besides chromosomal normality, endometrial receptivity is an important factor in determining successful pregnancies. Endometrial receptivity array (ERA), a promising endometrial receptivity test, was speculated to improve the reproductive outcomes. However, its effectiveness is controversial in clin...
| Main Authors: | , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Frontiers Media S.A.
2023-10-01
|
| Series: | Frontiers in Endocrinology |
| Subjects: | |
| Online Access: | https://www.frontiersin.org/articles/10.3389/fendo.2023.1251699/full |
| _version_ | 1797648446136516608 |
|---|---|
| author | Youwen Mei Yacong Wang Xue Ke Xuefei Liang Yonghong Lin Fang Wang |
| author_facet | Youwen Mei Yacong Wang Xue Ke Xuefei Liang Yonghong Lin Fang Wang |
| author_sort | Youwen Mei |
| collection | DOAJ |
| description | Besides chromosomal normality, endometrial receptivity is an important factor in determining successful pregnancies. Endometrial receptivity array (ERA), a promising endometrial receptivity test, was speculated to improve the reproductive outcomes. However, its effectiveness is controversial in clinical practice. Therefore, we conducted this review to investigate its role in in vitro fertilization (IVF) treatment. To eliminate the interference of embryo quality, we only analyzed studies that originally reported the reproductive outcomes of patients who underwent ERA-guided euploid embryo transfer (EET). Unexpectedly, it revealed that ERA could not optimize the reproductive outcomes in EET cycles, no matter in general infertile population or in patients with a history of previous failed embryo transfers. |
| first_indexed | 2024-03-11T15:32:15Z |
| format | Article |
| id | doaj.art-8dcfe64dc721415bb6c40efc00ddb050 |
| institution | Directory Open Access Journal |
| issn | 1664-2392 |
| language | English |
| last_indexed | 2024-03-11T15:32:15Z |
| publishDate | 2023-10-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Endocrinology |
| spelling | doaj.art-8dcfe64dc721415bb6c40efc00ddb0502023-10-27T02:21:18ZengFrontiers Media S.A.Frontiers in Endocrinology1664-23922023-10-011410.3389/fendo.2023.12516991251699Does endometrial receptivity array improve reproductive outcomes in euploid embryo transfer cycles? a systematic reviewYouwen MeiYacong WangXue KeXuefei LiangYonghong LinFang WangBesides chromosomal normality, endometrial receptivity is an important factor in determining successful pregnancies. Endometrial receptivity array (ERA), a promising endometrial receptivity test, was speculated to improve the reproductive outcomes. However, its effectiveness is controversial in clinical practice. Therefore, we conducted this review to investigate its role in in vitro fertilization (IVF) treatment. To eliminate the interference of embryo quality, we only analyzed studies that originally reported the reproductive outcomes of patients who underwent ERA-guided euploid embryo transfer (EET). Unexpectedly, it revealed that ERA could not optimize the reproductive outcomes in EET cycles, no matter in general infertile population or in patients with a history of previous failed embryo transfers.https://www.frontiersin.org/articles/10.3389/fendo.2023.1251699/fullendometrial receptivity arrayeuploid embryo transferin vitro fertilizationrecurrent implantation failurereproductive outcomes |
| spellingShingle | Youwen Mei Yacong Wang Xue Ke Xuefei Liang Yonghong Lin Fang Wang Does endometrial receptivity array improve reproductive outcomes in euploid embryo transfer cycles? a systematic review Frontiers in Endocrinology endometrial receptivity array euploid embryo transfer in vitro fertilization recurrent implantation failure reproductive outcomes |
| title | Does endometrial receptivity array improve reproductive outcomes in euploid embryo transfer cycles? a systematic review |
| title_full | Does endometrial receptivity array improve reproductive outcomes in euploid embryo transfer cycles? a systematic review |
| title_fullStr | Does endometrial receptivity array improve reproductive outcomes in euploid embryo transfer cycles? a systematic review |
| title_full_unstemmed | Does endometrial receptivity array improve reproductive outcomes in euploid embryo transfer cycles? a systematic review |
| title_short | Does endometrial receptivity array improve reproductive outcomes in euploid embryo transfer cycles? a systematic review |
| title_sort | does endometrial receptivity array improve reproductive outcomes in euploid embryo transfer cycles a systematic review |
| topic | endometrial receptivity array euploid embryo transfer in vitro fertilization recurrent implantation failure reproductive outcomes |
| url | https://www.frontiersin.org/articles/10.3389/fendo.2023.1251699/full |
| work_keys_str_mv | AT youwenmei doesendometrialreceptivityarrayimprovereproductiveoutcomesineuploidembryotransfercyclesasystematicreview AT yacongwang doesendometrialreceptivityarrayimprovereproductiveoutcomesineuploidembryotransfercyclesasystematicreview AT xueke doesendometrialreceptivityarrayimprovereproductiveoutcomesineuploidembryotransfercyclesasystematicreview AT xuefeiliang doesendometrialreceptivityarrayimprovereproductiveoutcomesineuploidembryotransfercyclesasystematicreview AT yonghonglin doesendometrialreceptivityarrayimprovereproductiveoutcomesineuploidembryotransfercyclesasystematicreview AT fangwang doesendometrialreceptivityarrayimprovereproductiveoutcomesineuploidembryotransfercyclesasystematicreview |