MarrowQuant Across Aging and Aplasia: A Digital Pathology Workflow for Quantification of Bone Marrow Compartments in Histological Sections

MarrowQuant Across Aging and Aplasia: A Digital Pathology Workflow for Quantification of Bone Marrow Compartments in Histological Sections

The bone marrow (BM) exists heterogeneously as hematopoietic/red or adipocytic/yellow marrow depending on skeletal location, age, and physiological condition. Mouse models and patients undergoing radio/chemotherapy or suffering acute BM failure endure rapid adipocytic conversion of the marrow microe...

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Bibliographic Details
Main Authors: Josefine Tratwal, David Bekri, Chiheb Boussema, Rita Sarkis, Nicolas Kunz, Tereza Koliqi, Shanti Rojas-Sutterlin, Frédérica Schyrr, Daniel Naveed Tavakol, Vasco Campos, Erica L. Scheller, Rossella Sarro, Carmen Bárcena, Bettina Bisig, Valentina Nardi, Laurence de Leval, Olivier Burri, Olaia Naveiras
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-09-01
Series:Frontiers in Endocrinology
Subjects:
bone marrow
hematoxylin and eosin
histology
adipocyte
pathology
skeleton
Online Access:https://www.frontiersin.org/article/10.3389/fendo.2020.00480/full

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