Fever of Unknown Origin: A Patient with Intermittent Idiopathic Fever for Three Years
Fever of unknown origin (FUO) is defined as a fever ≥38.3 ºC on at least three occasions over a period of at least three weeks, with no obvious diagnosis despite one week of inpatient investigations. Over 200 infections, neoplasm and inflammatory diseases can lead to an FUO. The definition of FUO is...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
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Galenos Yayinevi
2020-11-01
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| Series: | İstanbul Medical Journal |
| Subjects: | |
| Online Access: |
http://istanbulmedicaljournal.org/archives/archive-detail/article-preview/fever-of-unknown-origin-a-patient-with-ntermittent/41906
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| _version_ | 1828023139437641728 |
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| author | Esma Altunoğlu Doğan Can Çelik Sena Hekimoğlu Enes Özsoy Mehmet Hilmi Doğu |
| author_facet | Esma Altunoğlu Doğan Can Çelik Sena Hekimoğlu Enes Özsoy Mehmet Hilmi Doğu |
| author_sort | Esma Altunoğlu |
| collection | DOAJ |
| description | Fever of unknown origin (FUO) is defined as a fever ≥38.3 ºC on at least three occasions over a period of at least three weeks, with no obvious diagnosis despite one week of inpatient investigations. Over 200 infections, neoplasm and inflammatory diseases can lead to an FUO. The definition of FUO is difficult, even though more sophisticated diagnostic tools such as positron emitted tomography and many biochemical and serological assays have become routinely available. However, it is surprising that despite the improvement in diagnostic modalities, some FUO still remain undiagnosed. When the diagnosis of FUO was not defined, invasive tests such as biopsies may be useful. Bone marrow biopsy is an accepted method in FUO to uncover haematological malignancies and certain infections. We report a case of prolonged fever 4-5 times each year for 3 years which has presented FUO. She had bone morrow biopsy and was diagnosed with T-cell large granular lymphocytic leukaemia. |
| first_indexed | 2024-04-10T12:22:16Z |
| format | Article |
| id | doaj.art-8dd6e7904d4449448f908f66970c5312 |
| institution | Directory Open Access Journal |
| issn | 2619-9793 2148-094X |
| language | English |
| last_indexed | 2024-04-10T12:22:16Z |
| publishDate | 2020-11-01 |
| publisher | Galenos Yayinevi |
| record_format | Article |
| series | İstanbul Medical Journal |
| spelling | doaj.art-8dd6e7904d4449448f908f66970c53122023-02-15T16:15:25ZengGalenos Yayineviİstanbul Medical Journal2619-97932148-094X2020-11-01211232510.4274/imj.galenos.2020.7108413049054Fever of Unknown Origin: A Patient with Intermittent Idiopathic Fever for Three YearsEsma Altunoğlu0Doğan Can Çelik1Sena Hekimoğlu2Enes Özsoy3Mehmet Hilmi Doğu4 University of Health Sciences Turkey, İstanbul Training and Research Hospital, Clinic of Internal Medicine, İstanbul, Turkey University of Health Sciences Turkey, İstanbul Training and Research Hospital, Clinic of Internal Medicine, İstanbul, Turkey University of Health Sciences Turkey, İstanbul Training and Research Hospital, Clinic of Internal Medicine, İstanbul, Turkey University of Health Sciences Turkey, İstanbul Training and Research Hospital, Clinic of Internal Medicine, İstanbul, Turkey University of Health Sciences Turkey, İstanbul Training and Research Hospital, Clinic of Hematology, İstanbul, Turkey Fever of unknown origin (FUO) is defined as a fever ≥38.3 ºC on at least three occasions over a period of at least three weeks, with no obvious diagnosis despite one week of inpatient investigations. Over 200 infections, neoplasm and inflammatory diseases can lead to an FUO. The definition of FUO is difficult, even though more sophisticated diagnostic tools such as positron emitted tomography and many biochemical and serological assays have become routinely available. However, it is surprising that despite the improvement in diagnostic modalities, some FUO still remain undiagnosed. When the diagnosis of FUO was not defined, invasive tests such as biopsies may be useful. Bone marrow biopsy is an accepted method in FUO to uncover haematological malignancies and certain infections. We report a case of prolonged fever 4-5 times each year for 3 years which has presented FUO. She had bone morrow biopsy and was diagnosed with T-cell large granular lymphocytic leukaemia. http://istanbulmedicaljournal.org/archives/archive-detail/article-preview/fever-of-unknown-origin-a-patient-with-ntermittent/41906 fever of unknown originbone morrow biopsyleukemia |
| spellingShingle | Esma Altunoğlu Doğan Can Çelik Sena Hekimoğlu Enes Özsoy Mehmet Hilmi Doğu Fever of Unknown Origin: A Patient with Intermittent Idiopathic Fever for Three Years İstanbul Medical Journal fever of unknown origin bone morrow biopsy leukemia |
| title | Fever of Unknown Origin: A Patient with Intermittent Idiopathic Fever for Three Years |
| title_full | Fever of Unknown Origin: A Patient with Intermittent Idiopathic Fever for Three Years |
| title_fullStr | Fever of Unknown Origin: A Patient with Intermittent Idiopathic Fever for Three Years |
| title_full_unstemmed | Fever of Unknown Origin: A Patient with Intermittent Idiopathic Fever for Three Years |
| title_short | Fever of Unknown Origin: A Patient with Intermittent Idiopathic Fever for Three Years |
| title_sort | fever of unknown origin a patient with intermittent idiopathic fever for three years |
| topic | fever of unknown origin bone morrow biopsy leukemia |
| url |
http://istanbulmedicaljournal.org/archives/archive-detail/article-preview/fever-of-unknown-origin-a-patient-with-ntermittent/41906
|
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