Herpes Simplex Virus, Cytomegalovirus, and Pneumonia in a Treatment-Naive HIV-Positive Patient with Pulmonary Alveolar Proteinosis: Case Report

Infection with multiple pathogens concurrently has become less common since the introduction of potent antiretroviral agent and effective prophylactic agents. We describe a patient with pulmonary alveolar proteinosis (PAP) admitted with pneumonia who was found to have AIDS and diagnosed with Pneumoc...

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Main Authors: Anita Bapat MD, Eliahu Bishburg MD, Sandhya Nagarakanti MD
Format: Article
Language:English
Published: SAGE Publishing 2017-07-01
Series:Journal of the International Association of Providers of AIDS Care
Online Access:https://doi.org/10.1177/2325957417702488
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author Anita Bapat MD
Eliahu Bishburg MD
Sandhya Nagarakanti MD
author_facet Anita Bapat MD
Eliahu Bishburg MD
Sandhya Nagarakanti MD
author_sort Anita Bapat MD
collection DOAJ
description Infection with multiple pathogens concurrently has become less common since the introduction of potent antiretroviral agent and effective prophylactic agents. We describe a patient with pulmonary alveolar proteinosis (PAP) admitted with pneumonia who was found to have AIDS and diagnosed with Pneumocystis jiroveci pneumonia, human herpesvirus type 1 (HHV-1), and a concomitant cytomegalovirus viremia. Polymerase chain reaction viral load was used for diagnosis of HHV-1 and follow-up. The patient was treated with trimethoprim–sulfamethoxazole and ganciclovir and had a resolution of pneumonia. Since patients with PAP who are diagnosed as having AIDS could be concomitantly infected with multiple pathogens, rapid accurate diagnosis and treatment may have a positive effect on outcome.
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spelling doaj.art-8dd7b95567a24ca08d8a360f9d450f632022-12-21T23:48:31ZengSAGE PublishingJournal of the International Association of Providers of AIDS Care2325-95742325-95822017-07-011610.1177/2325957417702488Herpes Simplex Virus, Cytomegalovirus, and Pneumonia in a Treatment-Naive HIV-Positive Patient with Pulmonary Alveolar Proteinosis: Case ReportAnita Bapat MD0Eliahu Bishburg MD1Sandhya Nagarakanti MD2 Division of Infectious Disease, Newark Beth Israel Medical Center, Newark, NJ, USA Division of Infectious Disease, Newark Beth Israel Medical Center, Newark, NJ, USA Division of Infectious Disease, Newark Beth Israel Medical Center, Newark, NJ, USAInfection with multiple pathogens concurrently has become less common since the introduction of potent antiretroviral agent and effective prophylactic agents. We describe a patient with pulmonary alveolar proteinosis (PAP) admitted with pneumonia who was found to have AIDS and diagnosed with Pneumocystis jiroveci pneumonia, human herpesvirus type 1 (HHV-1), and a concomitant cytomegalovirus viremia. Polymerase chain reaction viral load was used for diagnosis of HHV-1 and follow-up. The patient was treated with trimethoprim–sulfamethoxazole and ganciclovir and had a resolution of pneumonia. Since patients with PAP who are diagnosed as having AIDS could be concomitantly infected with multiple pathogens, rapid accurate diagnosis and treatment may have a positive effect on outcome.https://doi.org/10.1177/2325957417702488
spellingShingle Anita Bapat MD
Eliahu Bishburg MD
Sandhya Nagarakanti MD
Herpes Simplex Virus, Cytomegalovirus, and Pneumonia in a Treatment-Naive HIV-Positive Patient with Pulmonary Alveolar Proteinosis: Case Report
Journal of the International Association of Providers of AIDS Care
title Herpes Simplex Virus, Cytomegalovirus, and Pneumonia in a Treatment-Naive HIV-Positive Patient with Pulmonary Alveolar Proteinosis: Case Report
title_full Herpes Simplex Virus, Cytomegalovirus, and Pneumonia in a Treatment-Naive HIV-Positive Patient with Pulmonary Alveolar Proteinosis: Case Report
title_fullStr Herpes Simplex Virus, Cytomegalovirus, and Pneumonia in a Treatment-Naive HIV-Positive Patient with Pulmonary Alveolar Proteinosis: Case Report
title_full_unstemmed Herpes Simplex Virus, Cytomegalovirus, and Pneumonia in a Treatment-Naive HIV-Positive Patient with Pulmonary Alveolar Proteinosis: Case Report
title_short Herpes Simplex Virus, Cytomegalovirus, and Pneumonia in a Treatment-Naive HIV-Positive Patient with Pulmonary Alveolar Proteinosis: Case Report
title_sort herpes simplex virus cytomegalovirus and pneumonia in a treatment naive hiv positive patient with pulmonary alveolar proteinosis case report
url https://doi.org/10.1177/2325957417702488
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