Current Knowledge on Beetroot Bioactive Compounds: Role of Nitrate and Betalains in Health and Disease

An increase in the prevalence of noncommunicable chronic diseases has been occurring in recent decades. Among the deaths resulting from these conditions, cardiovascular diseases (CVD) stand out as the main contributors. In this regard, dietary patterns featuring a high content of vegetables and frui...

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Main Authors: Iñaki Milton-Laskibar, J. Alfredo Martínez, María P. Portillo
Format: Article
Language:English
Published: MDPI AG 2021-06-01
Series:Foods
Subjects:
Online Access:https://www.mdpi.com/2304-8158/10/6/1314
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author Iñaki Milton-Laskibar
J. Alfredo Martínez
María P. Portillo
author_facet Iñaki Milton-Laskibar
J. Alfredo Martínez
María P. Portillo
author_sort Iñaki Milton-Laskibar
collection DOAJ
description An increase in the prevalence of noncommunicable chronic diseases has been occurring in recent decades. Among the deaths resulting from these conditions, cardiovascular diseases (CVD) stand out as the main contributors. In this regard, dietary patterns featuring a high content of vegetables and fruits, such as the Mediterranean and the DASH diets, are considered beneficial, and thus have been extensively studied. This has resulted in growing interest in vegetable-derived ingredients and food-supplements that may have potential therapeutic properties. Among these supplements, beetroot juice, which is obtained from the root vegetable <i>Beta vulgaris,</i> has gained much attention. Although a significant part of the interest in beetroot juice is due to its nitrate (NO<sub>3</sub><sup>−</sup>) content, which has demonstrated bioactivity in the cardiovascular system, other ingredients with potential beneficial properties such as polyphenols, pigments and organic acids are also present. In this context, the aim of this review article is to analyze the current knowledge regarding the benefits related to the consumption of beetroot and derived food-supplements. Therefore, this article focuses on nitrate and betalains, which are considered to be the major bioactive compounds present in beetroot, and thus in the derived dietary supplements.
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spelling doaj.art-8ddc83a60ef14d039bd6a57524acf1252023-11-21T23:08:52ZengMDPI AGFoods2304-81582021-06-01106131410.3390/foods10061314Current Knowledge on Beetroot Bioactive Compounds: Role of Nitrate and Betalains in Health and DiseaseIñaki Milton-Laskibar0J. Alfredo Martínez1María P. Portillo2Precision Nutrition and Cardiometabolic Health Program, IMDEA—Food Institute (Madrid Institute for Advanced Studies), Campus of International Excellence (CEI) UAM + CSIC, Spanish National Research Council, 28049 Madrid, SpainPrecision Nutrition and Cardiometabolic Health Program, IMDEA—Food Institute (Madrid Institute for Advanced Studies), Campus of International Excellence (CEI) UAM + CSIC, Spanish National Research Council, 28049 Madrid, SpainCIBERobn Physiopathology of Obesity and Nutrition, Institute of Health Carlos III (ISCIII), 28029 Madrid, SpainAn increase in the prevalence of noncommunicable chronic diseases has been occurring in recent decades. Among the deaths resulting from these conditions, cardiovascular diseases (CVD) stand out as the main contributors. In this regard, dietary patterns featuring a high content of vegetables and fruits, such as the Mediterranean and the DASH diets, are considered beneficial, and thus have been extensively studied. This has resulted in growing interest in vegetable-derived ingredients and food-supplements that may have potential therapeutic properties. Among these supplements, beetroot juice, which is obtained from the root vegetable <i>Beta vulgaris,</i> has gained much attention. Although a significant part of the interest in beetroot juice is due to its nitrate (NO<sub>3</sub><sup>−</sup>) content, which has demonstrated bioactivity in the cardiovascular system, other ingredients with potential beneficial properties such as polyphenols, pigments and organic acids are also present. In this context, the aim of this review article is to analyze the current knowledge regarding the benefits related to the consumption of beetroot and derived food-supplements. Therefore, this article focuses on nitrate and betalains, which are considered to be the major bioactive compounds present in beetroot, and thus in the derived dietary supplements.https://www.mdpi.com/2304-8158/10/6/1314beetrootdietary supplementnitratebetalains
spellingShingle Iñaki Milton-Laskibar
J. Alfredo Martínez
María P. Portillo
Current Knowledge on Beetroot Bioactive Compounds: Role of Nitrate and Betalains in Health and Disease
Foods
beetroot
dietary supplement
nitrate
betalains
title Current Knowledge on Beetroot Bioactive Compounds: Role of Nitrate and Betalains in Health and Disease
title_full Current Knowledge on Beetroot Bioactive Compounds: Role of Nitrate and Betalains in Health and Disease
title_fullStr Current Knowledge on Beetroot Bioactive Compounds: Role of Nitrate and Betalains in Health and Disease
title_full_unstemmed Current Knowledge on Beetroot Bioactive Compounds: Role of Nitrate and Betalains in Health and Disease
title_short Current Knowledge on Beetroot Bioactive Compounds: Role of Nitrate and Betalains in Health and Disease
title_sort current knowledge on beetroot bioactive compounds role of nitrate and betalains in health and disease
topic beetroot
dietary supplement
nitrate
betalains
url https://www.mdpi.com/2304-8158/10/6/1314
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AT jalfredomartinez currentknowledgeonbeetrootbioactivecompoundsroleofnitrateandbetalainsinhealthanddisease
AT mariapportillo currentknowledgeonbeetrootbioactivecompoundsroleofnitrateandbetalainsinhealthanddisease