Cytotoxic Tph subset with low B-cell helper functions and its involvement in systemic lupus erythematosus

Cytotoxic Tph subset with low B-cell helper functions and its involvement in systemic lupus erythematosus

Abstract T peripheral helper (Tph) cells are thought to contribute to extra-follicular B cell activation and play a pathogenic role in autoimmune diseases. However, the role of Tph subsets is not fully elucidated. Here, we investigate the immunological functions of Tph subsets and their involvement...

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Main Authors: Noriyasu Seki, Hideto Tsujimoto, Shuhei Tanemura, Shinji Kojima, Fumihiko Miyoshi, Jun Kikuchi, Shuntaro Saito, Mitsuhiro Akiyama, Kunio Sugahara, Keiko Yoshimoto, Yuko Kaneko, Kenji Chiba, Tsutomu Takeuchi
Format: Article
Language:English
Published: Nature Portfolio 2024-03-01
Series:Communications Biology
Online Access:https://doi.org/10.1038/s42003-024-05989-x

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