Study of correlations between metabolic risk factors, PWV and hypertension in college students
Objective: Obesity, dyslipidemia and diabetes have been recognized as risk factors of hypertension in the general population. This study focused on college students and correlations between serum lipids, serum uric acid, fasting plasma glucose, serum creatinine, body mass index, brachial-ankle pulse...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Taylor & Francis Group
2020-05-01
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| Series: | Clinical and Experimental Hypertension |
| Subjects: | |
| Online Access: | http://dx.doi.org/10.1080/10641963.2020.1723617 |
| _version_ | 1797681306359824384 |
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| author | Xiaoyi Ji Haiying Zhao Menglin Wang Yaru Li Chunli Zhang Xinyu Wang |
| author_facet | Xiaoyi Ji Haiying Zhao Menglin Wang Yaru Li Chunli Zhang Xinyu Wang |
| author_sort | Xiaoyi Ji |
| collection | DOAJ |
| description | Objective: Obesity, dyslipidemia and diabetes have been recognized as risk factors of hypertension in the general population. This study focused on college students and correlations between serum lipids, serum uric acid, fasting plasma glucose, serum creatinine, body mass index, brachial-ankle pulse wave velocity and hypertension. The results suggested that there was no relevance between serum lipids and hypertension. However, it came out that hypertension is associated with normal fasting plasma glucose, BMI (thinness and normal weight), normal serum creatinine. Methods: A total of 5185 students were enrolled, and their blood pressure, height and weight were measured. 285 of the students were selected to take physical examinations including serum uric acid, total cholesterol, low-density lipoprotein cholesterol, triglyceride, high-density lipoprotein cholesterol, fasting plasma glucose, serum creatinine, blood urea nitrogen, ankle-brachial index and brachial-ankle pulse wave velocity measured. Results: The values of systolic blood pressure(SBP), diastolic blood pressure(DBP), serum uric acid, fasting plasma glucose(FPG), serum creatinine, body mass index(BMI), and brachial-ankle pulse wave velocity(baPWV) were higher in hypertension group than those in non-hypertension group (P < .001, <0.001, <0.001, = 0.009, = 0.07, <0.001, <0.001, respectively). Logistic regression showed correlations between hypertension and hyperuricemia (OR = 2.975, 95%CI: 1.672–5.291), obesity (OR = 2.814, 95%CI: 1.297–6.105), fasting plasma glucose (OR = 2.184, 95%CI: 1.090–4.378) and brachial-ankle pulse wave velocity (OR = 1.005, 95%CI: 1.003–1.007). The AUC was 0.786 (95%CI: 0.729–0.842, P < .0001). We can draw a conclusion that hyperuricemia, obesity, fasting plasma glucose and brachial-ankle pulse wave velocity, listed in descending order of influence, are risk factors for hypertension in college students. |
| first_indexed | 2024-03-11T23:43:04Z |
| format | Article |
| id | doaj.art-8de08bcb27e440308ef53b4c30c58f44 |
| institution | Directory Open Access Journal |
| issn | 1064-1963 1525-6006 |
| language | English |
| last_indexed | 2024-03-11T23:43:04Z |
| publishDate | 2020-05-01 |
| publisher | Taylor & Francis Group |
| record_format | Article |
| series | Clinical and Experimental Hypertension |
| spelling | doaj.art-8de08bcb27e440308ef53b4c30c58f442023-09-19T15:19:29ZengTaylor & Francis GroupClinical and Experimental Hypertension1064-19631525-60062020-05-0142437638010.1080/10641963.2020.17236171723617Study of correlations between metabolic risk factors, PWV and hypertension in college studentsXiaoyi Ji0Haiying Zhao1Menglin Wang2Yaru Li3Chunli Zhang4Xinyu Wang5Henan University People’s HospitalHenan University People’s HospitalHenan University People’s HospitalHenan University People’s HospitalZhengzhou Yihe Hospital Affiliated to Henan UniversityHenan University People’s HospitalObjective: Obesity, dyslipidemia and diabetes have been recognized as risk factors of hypertension in the general population. This study focused on college students and correlations between serum lipids, serum uric acid, fasting plasma glucose, serum creatinine, body mass index, brachial-ankle pulse wave velocity and hypertension. The results suggested that there was no relevance between serum lipids and hypertension. However, it came out that hypertension is associated with normal fasting plasma glucose, BMI (thinness and normal weight), normal serum creatinine. Methods: A total of 5185 students were enrolled, and their blood pressure, height and weight were measured. 285 of the students were selected to take physical examinations including serum uric acid, total cholesterol, low-density lipoprotein cholesterol, triglyceride, high-density lipoprotein cholesterol, fasting plasma glucose, serum creatinine, blood urea nitrogen, ankle-brachial index and brachial-ankle pulse wave velocity measured. Results: The values of systolic blood pressure(SBP), diastolic blood pressure(DBP), serum uric acid, fasting plasma glucose(FPG), serum creatinine, body mass index(BMI), and brachial-ankle pulse wave velocity(baPWV) were higher in hypertension group than those in non-hypertension group (P < .001, <0.001, <0.001, = 0.009, = 0.07, <0.001, <0.001, respectively). Logistic regression showed correlations between hypertension and hyperuricemia (OR = 2.975, 95%CI: 1.672–5.291), obesity (OR = 2.814, 95%CI: 1.297–6.105), fasting plasma glucose (OR = 2.184, 95%CI: 1.090–4.378) and brachial-ankle pulse wave velocity (OR = 1.005, 95%CI: 1.003–1.007). The AUC was 0.786 (95%CI: 0.729–0.842, P < .0001). We can draw a conclusion that hyperuricemia, obesity, fasting plasma glucose and brachial-ankle pulse wave velocity, listed in descending order of influence, are risk factors for hypertension in college students.http://dx.doi.org/10.1080/10641963.2020.1723617college studentshypertensionrisk factorsuric acid |
| spellingShingle | Xiaoyi Ji Haiying Zhao Menglin Wang Yaru Li Chunli Zhang Xinyu Wang Study of correlations between metabolic risk factors, PWV and hypertension in college students Clinical and Experimental Hypertension college students hypertension risk factors uric acid |
| title | Study of correlations between metabolic risk factors, PWV and hypertension in college students |
| title_full | Study of correlations between metabolic risk factors, PWV and hypertension in college students |
| title_fullStr | Study of correlations between metabolic risk factors, PWV and hypertension in college students |
| title_full_unstemmed | Study of correlations between metabolic risk factors, PWV and hypertension in college students |
| title_short | Study of correlations between metabolic risk factors, PWV and hypertension in college students |
| title_sort | study of correlations between metabolic risk factors pwv and hypertension in college students |
| topic | college students hypertension risk factors uric acid |
| url | http://dx.doi.org/10.1080/10641963.2020.1723617 |
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