FoxP3+ CD8 T-cells in acute HIV infection and following early antiretroviral therapy initiation

FoxP3+ CD8 T-cells in acute HIV infection and following early antiretroviral therapy initiation

ObjectivesBesides CD4 regulatory T-cells (Tregs), immunosuppressor FoxP3+ CD8 T-cells are emerging as an important subset of Tregs, which contribute to immune dysfunction and disease progression in HIV infection. However, FoxP3+ CD8 T-cell dynamics in acute HIV infection and following early antiretr...

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Bibliographic Details
Main Authors:	Alexis Yero, Tao Shi, Jean-Pierre Routy, Cécile Tremblay, Madeleine Durand, Cecilia T. Costiniuk, Mohammad-Ali Jenabian
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2022-07-01
Series:	Frontiers in Immunology
Subjects:	CD8 regulatory T cells (CD8 Tregs) acute HIV infection early antiretroviral therapy (ART) FoxP3 TGF-β1 CD39
Online Access:	https://www.frontiersin.org/articles/10.3389/fimmu.2022.962912/full

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