(1R,3S,5R,6S)-6-Hydroxy-3-tosyloxytropan-8-ium chloride
The title compound, C15H22NO4S+·Cl−, is a hydrolysis product of lesatropane [(1R,3S,5R,6S)-6-acetoxy-3-tosyloxytropane] hydrochloride, a potential antiglaucoma agent. As in lesatropane, the piperidine and pyrrolidine rings in the title compound adopt chair and envelope con...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
| Published: |
International Union of Crystallography
2010-02-01
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| Series: | Acta Crystallographica Section E |
| Online Access: | http://scripts.iucr.org/cgi-bin/paper?S1600536809055366 |
| _version_ | 1819279899411611648 |
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| author | Nian-Xi Yu Li-Min Yang Yang Lu |
| author_facet | Nian-Xi Yu Li-Min Yang Yang Lu |
| author_sort | Nian-Xi Yu |
| collection | DOAJ |
| description | The title compound, C15H22NO4S+·Cl−, is a hydrolysis product of lesatropane [(1R,3S,5R,6S)-6-acetoxy-3-tosyloxytropane] hydrochloride, a potential antiglaucoma agent. As in lesatropane, the piperidine and pyrrolidine rings in the title compound adopt chair and envelope conformations, respectively. There are two molecules in the unit cell with similar conformations. The crystal structure is stabilized by intermolecular O—H...Cl and N—H...Cl hydrogen bonds. |
| first_indexed | 2024-12-24T00:35:14Z |
| format | Article |
| id | doaj.art-8de295b2582944d788951976f7ad21b6 |
| institution | Directory Open Access Journal |
| issn | 1600-5368 |
| language | English |
| last_indexed | 2024-12-24T00:35:14Z |
| publishDate | 2010-02-01 |
| publisher | International Union of Crystallography |
| record_format | Article |
| series | Acta Crystallographica Section E |
| spelling | doaj.art-8de295b2582944d788951976f7ad21b62022-12-21T17:24:05ZengInternational Union of CrystallographyActa Crystallographica Section E1600-53682010-02-01662o317o31710.1107/S1600536809055366(1R,3S,5R,6S)-6-Hydroxy-3-tosyloxytropan-8-ium chlorideNian-Xi YuLi-Min YangYang LuThe title compound, C15H22NO4S+·Cl−, is a hydrolysis product of lesatropane [(1R,3S,5R,6S)-6-acetoxy-3-tosyloxytropane] hydrochloride, a potential antiglaucoma agent. As in lesatropane, the piperidine and pyrrolidine rings in the title compound adopt chair and envelope conformations, respectively. There are two molecules in the unit cell with similar conformations. The crystal structure is stabilized by intermolecular O—H...Cl and N—H...Cl hydrogen bonds.http://scripts.iucr.org/cgi-bin/paper?S1600536809055366 |
| spellingShingle | Nian-Xi Yu Li-Min Yang Yang Lu (1R,3S,5R,6S)-6-Hydroxy-3-tosyloxytropan-8-ium chloride Acta Crystallographica Section E |
| title | (1R,3S,5R,6S)-6-Hydroxy-3-tosyloxytropan-8-ium chloride |
| title_full | (1R,3S,5R,6S)-6-Hydroxy-3-tosyloxytropan-8-ium chloride |
| title_fullStr | (1R,3S,5R,6S)-6-Hydroxy-3-tosyloxytropan-8-ium chloride |
| title_full_unstemmed | (1R,3S,5R,6S)-6-Hydroxy-3-tosyloxytropan-8-ium chloride |
| title_short | (1R,3S,5R,6S)-6-Hydroxy-3-tosyloxytropan-8-ium chloride |
| title_sort | 1r 3s 5r 6s 6 hydroxy 3 tosyloxytropan 8 ium chloride |
| url | http://scripts.iucr.org/cgi-bin/paper?S1600536809055366 |
| work_keys_str_mv | AT nianxiyu 1r3s5r6s6hydroxy3tosyloxytropan8iumchloride AT liminyang 1r3s5r6s6hydroxy3tosyloxytropan8iumchloride AT yanglu 1r3s5r6s6hydroxy3tosyloxytropan8iumchloride |