Effect of Caffeine and Vitamin D3 on Body Weight of Balb/C Mice
Background: To evaluate effect of caffeine and vitamin D3 on body weight of BALB/c mice. Methods: In this experimental study thirty BALB/c mice, three weeks old with average weight 12-14 g were taken and divided into three groups with 10 mice (5 male, 5 female) in each group. The control group G1 wa...
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| Format: | Article |
| Language: | English |
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Rawalpindi Medical University
2016-12-01
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| Series: | Journal of Rawalpindi Medical College |
| Subjects: | |
| Online Access: | https://www.journalrmc.com/index.php/JRMC/article/view/160 |
| _version_ | 1818751500357206016 |
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| author | Maimoona Khan |
| author_facet | Maimoona Khan |
| author_sort | Maimoona Khan |
| collection | DOAJ |
| description | Background: To evaluate effect of caffeine and
vitamin D3 on body weight of BALB/c mice.
Methods: In this experimental study thirty BALB/c
mice, three weeks old with average weight 12-14 g
were taken and divided into three groups with 10
mice (5 male, 5 female) in each group. The control
group G1 was given normal diet prepared at National
Institute of Health Islamabad with liberal water
intake. Each animal in experimental group G2 was
given 10mg of caffeine per100g body weight on
alternate day, three days in a week by oral gavage for
60 days. All animals of G3 were given caffeine
10mg/100g body weight on alternate day, three days
a week and vitamin D3 0.1μg per day by oral gavage
for 60 days. The effect of caffeine and vitamin D3
was assessed by measuring the body weight of the
mice at the end of the experiment.
Results: Mean final body weight of mice of control
group G1 was 31.2 ± 1.932 g while the mean final
body weight of experimental groups G2 and G3 was
found to be 27.1 ± 2.025 g and 29.2 ± 2.098 g . Mean
final body weight of mice of experimental group G2
was less as compared to control group G1 and
experimental group G3.
Conclusion: The body weight of the mice was
reduced due to caffeine consumption while vitamin
D3 administration ameliorated the deleterious effect
of caffeine on the body weight. |
| first_indexed | 2024-12-18T04:36:33Z |
| format | Article |
| id | doaj.art-8de58cd441584c278db3f7f4baa6de35 |
| institution | Directory Open Access Journal |
| issn | 1683-3562 1683-3570 |
| language | English |
| last_indexed | 2024-12-18T04:36:33Z |
| publishDate | 2016-12-01 |
| publisher | Rawalpindi Medical University |
| record_format | Article |
| series | Journal of Rawalpindi Medical College |
| spelling | doaj.art-8de58cd441584c278db3f7f4baa6de352022-12-21T21:20:51ZengRawalpindi Medical UniversityJournal of Rawalpindi Medical College1683-35621683-35702016-12-01204Effect of Caffeine and Vitamin D3 on Body Weight of Balb/C MiceMaimoona Khan0Department of Anatomy,Army Medical College, RawalpindiBackground: To evaluate effect of caffeine and vitamin D3 on body weight of BALB/c mice. Methods: In this experimental study thirty BALB/c mice, three weeks old with average weight 12-14 g were taken and divided into three groups with 10 mice (5 male, 5 female) in each group. The control group G1 was given normal diet prepared at National Institute of Health Islamabad with liberal water intake. Each animal in experimental group G2 was given 10mg of caffeine per100g body weight on alternate day, three days in a week by oral gavage for 60 days. All animals of G3 were given caffeine 10mg/100g body weight on alternate day, three days a week and vitamin D3 0.1μg per day by oral gavage for 60 days. The effect of caffeine and vitamin D3 was assessed by measuring the body weight of the mice at the end of the experiment. Results: Mean final body weight of mice of control group G1 was 31.2 ± 1.932 g while the mean final body weight of experimental groups G2 and G3 was found to be 27.1 ± 2.025 g and 29.2 ± 2.098 g . Mean final body weight of mice of experimental group G2 was less as compared to control group G1 and experimental group G3. Conclusion: The body weight of the mice was reduced due to caffeine consumption while vitamin D3 administration ameliorated the deleterious effect of caffeine on the body weight.https://www.journalrmc.com/index.php/JRMC/article/view/160Body weightCaffeineVitamin D |
| spellingShingle | Maimoona Khan Effect of Caffeine and Vitamin D3 on Body Weight of Balb/C Mice Journal of Rawalpindi Medical College Body weight Caffeine Vitamin D |
| title | Effect of Caffeine and Vitamin D3 on Body Weight of Balb/C Mice |
| title_full | Effect of Caffeine and Vitamin D3 on Body Weight of Balb/C Mice |
| title_fullStr | Effect of Caffeine and Vitamin D3 on Body Weight of Balb/C Mice |
| title_full_unstemmed | Effect of Caffeine and Vitamin D3 on Body Weight of Balb/C Mice |
| title_short | Effect of Caffeine and Vitamin D3 on Body Weight of Balb/C Mice |
| title_sort | effect of caffeine and vitamin d3 on body weight of balb c mice |
| topic | Body weight Caffeine Vitamin D |
| url | https://www.journalrmc.com/index.php/JRMC/article/view/160 |
| work_keys_str_mv | AT maimoonakhan effectofcaffeineandvitamind3onbodyweightofbalbcmice |