Tissue engineering for the repair of peripheral nerve injury

Peripheral nerve injury is a common clinical problem and affects the quality of life of patients. Traditional restoration methods are not satisfactory. Researchers increasingly focus on the field of tissue engineering. The three key points in establishing a tissue engineering material are the biolog...

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Main Authors: Pei-Xun Zhang, Na Han, Yu-Hui Kou, Qing-Tang Zhu, Xiao-Lin Liu, Da-Ping Quan, Jian-Guo Chen, Bao-Guo Jiang
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2019-01-01
Series:Neural Regeneration Research
Subjects:
Online Access:http://www.nrronline.org/article.asp?issn=1673-5374;year=2019;volume=14;issue=1;spage=51;epage=58;aulast=Zhang
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author Pei-Xun Zhang
Na Han
Yu-Hui Kou
Qing-Tang Zhu
Xiao-Lin Liu
Da-Ping Quan
Jian-Guo Chen
Bao-Guo Jiang
author_facet Pei-Xun Zhang
Na Han
Yu-Hui Kou
Qing-Tang Zhu
Xiao-Lin Liu
Da-Ping Quan
Jian-Guo Chen
Bao-Guo Jiang
author_sort Pei-Xun Zhang
collection DOAJ
description Peripheral nerve injury is a common clinical problem and affects the quality of life of patients. Traditional restoration methods are not satisfactory. Researchers increasingly focus on the field of tissue engineering. The three key points in establishing a tissue engineering material are the biological scaffold material, the seed cells and various growth factors. Understanding the type of nerve injury, the construction of scaffold and the process of repair are necessary to solve peripheral nerve injury and promote its regeneration. This review describes the categories of peripheral nerve injury, fundamental research of peripheral nervous tissue engineering and clinical research on peripheral nerve scaffold material, and paves a way for related research and the use of conduits in clinical practice.
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spelling doaj.art-8de79a51b1f44bfdbf45fb770eee667f2022-12-21T18:52:47ZengWolters Kluwer Medknow PublicationsNeural Regeneration Research1673-53742019-01-01141515810.4103/1673-5374.243701Tissue engineering for the repair of peripheral nerve injuryPei-Xun ZhangNa HanYu-Hui KouQing-Tang ZhuXiao-Lin LiuDa-Ping QuanJian-Guo ChenBao-Guo JiangPeripheral nerve injury is a common clinical problem and affects the quality of life of patients. Traditional restoration methods are not satisfactory. Researchers increasingly focus on the field of tissue engineering. The three key points in establishing a tissue engineering material are the biological scaffold material, the seed cells and various growth factors. Understanding the type of nerve injury, the construction of scaffold and the process of repair are necessary to solve peripheral nerve injury and promote its regeneration. This review describes the categories of peripheral nerve injury, fundamental research of peripheral nervous tissue engineering and clinical research on peripheral nerve scaffold material, and paves a way for related research and the use of conduits in clinical practice.http://www.nrronline.org/article.asp?issn=1673-5374;year=2019;volume=14;issue=1;spage=51;epage=58;aulast=Zhangnerve regeneration; scaffold; biomaterial; stem cells; nerve growth factor; peripheral nerve injury; peripheral nerve repair; tissue engineering; neural regeneration
spellingShingle Pei-Xun Zhang
Na Han
Yu-Hui Kou
Qing-Tang Zhu
Xiao-Lin Liu
Da-Ping Quan
Jian-Guo Chen
Bao-Guo Jiang
Tissue engineering for the repair of peripheral nerve injury
Neural Regeneration Research
nerve regeneration; scaffold; biomaterial; stem cells; nerve growth factor; peripheral nerve injury; peripheral nerve repair; tissue engineering; neural regeneration
title Tissue engineering for the repair of peripheral nerve injury
title_full Tissue engineering for the repair of peripheral nerve injury
title_fullStr Tissue engineering for the repair of peripheral nerve injury
title_full_unstemmed Tissue engineering for the repair of peripheral nerve injury
title_short Tissue engineering for the repair of peripheral nerve injury
title_sort tissue engineering for the repair of peripheral nerve injury
topic nerve regeneration; scaffold; biomaterial; stem cells; nerve growth factor; peripheral nerve injury; peripheral nerve repair; tissue engineering; neural regeneration
url http://www.nrronline.org/article.asp?issn=1673-5374;year=2019;volume=14;issue=1;spage=51;epage=58;aulast=Zhang
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AT qingtangzhu tissueengineeringfortherepairofperipheralnerveinjury
AT xiaolinliu tissueengineeringfortherepairofperipheralnerveinjury
AT dapingquan tissueengineeringfortherepairofperipheralnerveinjury
AT jianguochen tissueengineeringfortherepairofperipheralnerveinjury
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