Assessing the impact of omega-3 fatty acids on ventricular tachyarrhythmia and survival in patients with ICDs: A systematic review and meta-analysis
Background: Recent studies investigating the effects of fish oil on shocks administered by ICDs in patients with ventricular tachycardias produced inconclusive results. This systematic review aims to evaluate the effectiveness of omega-3 polyunsaturated fatty acids in lowering the risk of life-threa...
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| Format: | Article |
| Language: | English |
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Elsevier
2024-06-01
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| Series: | International Journal of Cardiology: Heart & Vasculature |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S2352906724000630 |
| _version_ | 1797230589178281984 |
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| author | Erfan Kohansal Amir Askarinejad MohammadHossein MozafaryBazargany Amirreza Sabahizadeh SeyedAbbas Pakmehr Majid Haghjoo |
| author_facet | Erfan Kohansal Amir Askarinejad MohammadHossein MozafaryBazargany Amirreza Sabahizadeh SeyedAbbas Pakmehr Majid Haghjoo |
| author_sort | Erfan Kohansal |
| collection | DOAJ |
| description | Background: Recent studies investigating the effects of fish oil on shocks administered by ICDs in patients with ventricular tachycardias produced inconclusive results. This systematic review aims to evaluate the effectiveness of omega-3 polyunsaturated fatty acids in lowering the risk of life-threatening VTs among individuals with implantable cardioverter-defibrillators. Methods: We searched five databases, including Central, PubMed, EMBASE, Web of Science, and Scopus, for studies evaluating the efficacy of omega-3 polyunsaturated fatty acids (PUFAs) for the prevention of ICD events for VT or VF, published up to December 1, 2023. Results: Four trials were finally included in the study. The pooled risk ratios for mortality and ICD events were 0.87 (95% CI:0.58–1.32) and 0.75 (95% CI:0.48–1.18), respectively. Conclusion: No significant effect was discovered to support the antiarrhythmic properties or survival advantages of n-3 polyunsaturated fatty acids (PUFA) in individuals with implanted implantable cardioverter-defibrillators (ICD). |
| first_indexed | 2024-04-24T15:30:53Z |
| format | Article |
| id | doaj.art-8df55d1118d440859e2f25a2269567d2 |
| institution | Directory Open Access Journal |
| issn | 2352-9067 |
| language | English |
| last_indexed | 2024-04-24T15:30:53Z |
| publishDate | 2024-06-01 |
| publisher | Elsevier |
| record_format | Article |
| series | International Journal of Cardiology: Heart & Vasculature |
| spelling | doaj.art-8df55d1118d440859e2f25a2269567d22024-04-02T04:15:17ZengElsevierInternational Journal of Cardiology: Heart & Vasculature2352-90672024-06-0152101397Assessing the impact of omega-3 fatty acids on ventricular tachyarrhythmia and survival in patients with ICDs: A systematic review and meta-analysisErfan Kohansal0Amir Askarinejad1MohammadHossein MozafaryBazargany2Amirreza Sabahizadeh3SeyedAbbas Pakmehr4Majid Haghjoo5Rajaie Cardiovascular Medical and Research Institute, Iran University of Medical Sciences, Tehran, IranRajaie Cardiovascular Medical and Research Institute, Iran University of Medical Sciences, Tehran, IranRajaie Cardiovascular Medical and Research Institute, Iran University of Medical Sciences, Tehran, IranSchool of Medicine, Shiraz University of Medical Sciences, Shiraz, IranSchool of Medicine, Shiraz University of Medical Sciences, Shiraz, IranDepartment of Cardiac Electrophysiology, Rajaie Cardiovascular Medical and Research Institute, Iran University of Medical Sciences, Tehran, Iran; Cardiac Electrophysiology Research Center, Rajaie Cardiovascular Medical and Research Institute, Iran University of Medical Sciences, Tehran, Iran; Corresponding author.Background: Recent studies investigating the effects of fish oil on shocks administered by ICDs in patients with ventricular tachycardias produced inconclusive results. This systematic review aims to evaluate the effectiveness of omega-3 polyunsaturated fatty acids in lowering the risk of life-threatening VTs among individuals with implantable cardioverter-defibrillators. Methods: We searched five databases, including Central, PubMed, EMBASE, Web of Science, and Scopus, for studies evaluating the efficacy of omega-3 polyunsaturated fatty acids (PUFAs) for the prevention of ICD events for VT or VF, published up to December 1, 2023. Results: Four trials were finally included in the study. The pooled risk ratios for mortality and ICD events were 0.87 (95% CI:0.58–1.32) and 0.75 (95% CI:0.48–1.18), respectively. Conclusion: No significant effect was discovered to support the antiarrhythmic properties or survival advantages of n-3 polyunsaturated fatty acids (PUFA) in individuals with implanted implantable cardioverter-defibrillators (ICD).http://www.sciencedirect.com/science/article/pii/S2352906724000630N-3 polyunsaturated fatty acidsVentricular tachycardiaImplantable cardioverter-defibrillatorOmega-3Fish oil |
| spellingShingle | Erfan Kohansal Amir Askarinejad MohammadHossein MozafaryBazargany Amirreza Sabahizadeh SeyedAbbas Pakmehr Majid Haghjoo Assessing the impact of omega-3 fatty acids on ventricular tachyarrhythmia and survival in patients with ICDs: A systematic review and meta-analysis International Journal of Cardiology: Heart & Vasculature N-3 polyunsaturated fatty acids Ventricular tachycardia Implantable cardioverter-defibrillator Omega-3 Fish oil |
| title | Assessing the impact of omega-3 fatty acids on ventricular tachyarrhythmia and survival in patients with ICDs: A systematic review and meta-analysis |
| title_full | Assessing the impact of omega-3 fatty acids on ventricular tachyarrhythmia and survival in patients with ICDs: A systematic review and meta-analysis |
| title_fullStr | Assessing the impact of omega-3 fatty acids on ventricular tachyarrhythmia and survival in patients with ICDs: A systematic review and meta-analysis |
| title_full_unstemmed | Assessing the impact of omega-3 fatty acids on ventricular tachyarrhythmia and survival in patients with ICDs: A systematic review and meta-analysis |
| title_short | Assessing the impact of omega-3 fatty acids on ventricular tachyarrhythmia and survival in patients with ICDs: A systematic review and meta-analysis |
| title_sort | assessing the impact of omega 3 fatty acids on ventricular tachyarrhythmia and survival in patients with icds a systematic review and meta analysis |
| topic | N-3 polyunsaturated fatty acids Ventricular tachycardia Implantable cardioverter-defibrillator Omega-3 Fish oil |
| url | http://www.sciencedirect.com/science/article/pii/S2352906724000630 |
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